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KAT2B 抗体

This anti-KAT2B antibody is a 兔 单克隆 antibody detecting KAT2B in WB, FACS 和 IF (cc). Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN6943859
发货至: 中国
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中国
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for KAT2B 抗体 (ABIN6943859)

抗原

See all KAT2B 抗体
KAT2B (K(lysine) Acetyltransferase 2B (KAT2B))

适用

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人, 小鼠, 大鼠

宿主

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克隆类型

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单克隆

标记

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This KAT2B antibody is un-conjugated

应用范围

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Western Blotting (WB), Flow Cytometry (FACS), Immunofluorescence (Cultured Cells) (IF (cc))

克隆位点

2C1
  • 交叉反应

    人, 小鼠, 大鼠

    纯化方法

    Purified by Protein A.

    免疫原

    Recombinant protein within human PCAF aa 100-300

    亚型

    IgG
  • 应用备注

    WB 1:300-5000
    FCM 1:20-100
    IF(ICC) 1:50-200

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    Aqueous buffered solution containing 1xTBS ( pH 7.4), 1 % BSA, 40 %Glycerol and 0.05 % Sodium Azide.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at 4°C for up to 2 weeks. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

    有效期

    12 months
  • 抗原

    KAT2B (K(lysine) Acetyltransferase 2B (KAT2B))

    别名

    KAT2B

    背景

    Synonyms: Histone acetyltransferase KAT2B, Histone acetyltransferase PCAF, Lysine acetyltransferase 2B, P300/CBP-associated factor, Histone acetylase PCAF, P/CAF, KAT2B, PCAF.

    Background: Functions as a histone acetyltransferase (HAT) to promote transcriptional activation. Has significant histone acetyltransferase activity with core histones (H3 and H4), and also with nucleosome core particles. Also acetylates non-histone proteins, such as ACLY, PLK4 and TBX5. Inhibits cell-cycle progression and counteracts the mitogenic activity of the adenoviral oncoprotein E1A. Acts as a circadian transcriptional coactivator which enhances the activity of the circadian transcriptional activators: NPAS2-ARNTL/BMAL1 and CLOCK-ARNTL/BMAL1 heterodimers. Involved in heart and limb development by mediating acetylation of TBX5, acetylation regulating nucleocytoplasmic shuttling of TBX5. Acts as a negative regulator of centrosome amplification by mediating acetylation of PLK4. Also acetylates spermidine.

    基因ID

    8850

    UniProt

    Q92831

    途径

    p53 Pathway, Regulation of Carbohydrate Metabolic Process
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