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CYP27B1 抗体 (AA 1-100) (Biotin)

CYP27B1 适用: 小鼠 WB, ELISA, IHC (p) 宿主: 兔 Polyclonal Biotin
产品编号 ABIN6942772
发货至: 中国
  • 抗原 See all CYP27B1 抗体
    CYP27B1 (Cytochrome P450, Family 27, Subfamily B, Polypeptide 1 (CYP27B1))
    抗原表位
    • 5
    • 5
    • 4
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1-100
    适用
    • 16
    • 9
    • 6
    • 5
    小鼠
    宿主
    • 28
    • 2
    克隆类型
    • 28
    • 2
    多克隆
    标记
    • 16
    • 5
    • 4
    • 4
    • 1
    This CYP27B1 antibody is conjugated to Biotin
    应用范围
    • 18
    • 18
    • 7
    • 6
    • 3
    • 3
    • 2
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    交叉反应
    小鼠
    预测反应
    Human,Rat,Dog,Cow,Sheep,Pig,Horse
    纯化方法
    Purified by Protein A.
    免疫原
    KLH conjugated synthetic peptide derived from human CYP27B1
    亚型
    IgG
    Top Product
    Discover our top product CYP27B1 Primary Antibody
  • 应用备注
    WB 1:300-5000
    IHC-P 1:200-400
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 μg/μL
    缓冲液
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C for 12 months.
    有效期
    12 months
  • 抗原
    CYP27B1 (Cytochrome P450, Family 27, Subfamily B, Polypeptide 1 (CYP27B1))
    别名
    CYP27B1 (CYP27B1 产品)
    别名
    cp2b antibody, cyp1 antibody, cyp1alpha antibody, cyp27b antibody, p450c1 antibody, pddr antibody, vdd1 antibody, vddr antibody, vddri antibody, vdr antibody, CP2B antibody, CYP1 antibody, CYP1alpha antibody, CYP27B antibody, P450c1 antibody, PDDR antibody, VDD1 antibody, VDDR antibody, VDDRI antibody, VDR antibody, Cyp40 antibody, Cp2b antibody, Cyp1 antibody, Cyp27b antibody, Pddr antibody, Vdd1 antibody, Vddr antibody, VddrI antibody, Vdr antibody, cytochrome P450 family 27 subfamily B member 1 antibody, cytochrome P450, family 27, subfamily B, polypeptide 1 antibody, cytochrome P450, family 27, subfamily b, polypeptide 1 antibody, cyp27b1 antibody, CYP27B1 antibody, Cyp27b1 antibody
    背景

    Synonyms: 1alpha(OH)ase, 25-hydroxyvitamin D(3) 1-alpha-hydroxylase, 25-hydroxyvitamin D-1 alpha hydroxylase, 25-OHD-1 alpha-hydroxylase, Calcidiol 1-monooxygenase, CP27B_HUMAN, CP2B, CYP1, CYP1ALPHA, CYP27B, Cyp27b1, Cytochrome p450 27B1, Cytochrome p450 27B13, Cytochrome P450 family 27 subfamily B polypeptide 1, Cytochrome P450 subfamily XXVIIB (25-hydroxyvitamin D-1-alpha-hydroxylase) polypeptide 1, Cytochrome P450 subfamily XXVIIB polypeptide 1, Cytochrome P450C1 alpha, Cytochrome P450VD1-alpha, mitochondrial, P450C1 alpha, P450c1, P450C1-alpha, P450VD1-alpha, PDDR, VD3 1A hydroxylase, VDD1, VDDR, VDDR I, VDDRI, VDR.

    Background: The cytochrome P450 proteins are monooxygenases that catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. P450 enzymes are classified into subfamilies based on their sequence similarities. CYP27B1, a 508-amino acid protein that belongs to the XXVIIB subfamily of the cytochrome P450 family, localizes to the mitochondrion and is expressed in the kidney. The CYP27B1 protein catalyzes the conversion of 25-hydroxyvitamin D3 (25(OH)D) to 1-alpha,25-dihydroxyvitamin D3 (1,25(OH)2D) and functions in calcium metabolism, normal bone growth, and tissue differentiation. Mutations in the gene which encodes for CYP27B1 cause vitamin D-dependent rickets type 1 (VDDR-1), also designated pseudovitamin D deficiency rickets (PDDR), an autosomal recessive disease characterized by early onset of rickets with hypocalcemia and muscle weakness.

    基因ID
    1594
    UniProt
    O15528
    途径
    Metabolism of Steroid Hormones and Vitamin D
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