Recombinant BAX 抗体 (AA 20-150)
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北京 101111
Quick Overview for Recombinant BAX 抗体 (AA 20-150) (ABIN6942235)
抗原
See all BAX 抗体抗体类型
适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 20-150
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原理
- Bax Recombinant Antibody
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交叉反应
- 人, 小鼠, 大鼠
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纯化方法
- Purified by Protein A.
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免疫原
- Recombinant human Bak between 20 to 150 amino acids
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亚型
- IgG
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应用备注
- WB(1:300-5000), IHC-P(1:20-100), IHC-F(1:200-400), IF(1:50-200), Flow-Cyt(1:50-200)
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- 0.01M TBS ( pH 7.4), 1 % BSA, 0.02 % Proclin 300, and 50 % Glycerol
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Shipped at 4°. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
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有效期
- 12 months
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- BAX (BCL2-Associated X Protein (BAX))
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别名
- Bax
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背景
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Synonyms: Apoptosis regulator BAX, Bcl-2-like protein 4, Bcl2-L-4, BCL2L4
Background: Accelerates programmed cell death by binding to, and antagonizing the apoptosis repressor BCL2 or its adenovirus homolog E1B 19k protein. Under stress conditions, undergoes a conformation change that causes translocation to the mitochondrion membrane, leading to the release of cytochrome c that then triggers apoptosis. Promotes activation of CASP3, and thereby apoptosis.
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基因ID
- 581
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UniProt
- Q07812
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途径
- p53 Pathway, PI3K-Akt Signaling, Apoptosis, Caspase Cascade in Apoptosis, Positive Regulation of Endopeptidase Activity, Unfolded Protein Response
抗原
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