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Recombinant Insulin 抗体

This anti-Insulin antibody is a 小鼠 单克隆 antibody detecting Insulin in IHC 和 StM. Suitable for 人, Pig, 小鼠, Cow 和 兔.
产品编号 ABIN6939797
发货至: 中国

Quick Overview for Recombinant Insulin 抗体 (ABIN6939797)

抗原

See all Insulin (INS) 抗体
Insulin (INS)

抗体类型

Recombinant Antibody

适用

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人, Pig, 小鼠, Cow, 兔

宿主

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小鼠

克隆类型

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单克隆

标记

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This Insulin antibody is un-conjugated

应用范围

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Immunohistochemistry (IHC), Staining Methods (StM)

克隆位点

RIRDN-805
  • 特异性

    Recognizes a polypeptide which is identified as insulin, a 51-amino acid polypeptide composed of A and B chains connected through the C-peptide. Proinsulin, which has very little biological activity, is cleaved by proteases within its cell of origin into the insulin molecule and the C-terminal basic residue. Insulin enhances membrane transport of glucose, amino acids, and certain ions. It also promotes glycogen storage, formation of triglycerides, and synthesis of proteins and nucleic acids. Deficiency of insulin results in diabetes mellitus. The main storage site for insulin is the pancreatic islets. Antibodies to insulin are important as beta-cell and insulinoma marker.

    纯化方法

    Purified by Protein A/G

    免疫原

    Recombinant full-length human Insulin protein

    亚型

    IgG1 kappa
  • 应用备注

    Positive Control: MIA PaCa-2 cells. Pancreas.

    Known Application: Immunohistochemistry (Formalin-fixed) (0.5-1 μg/mL for 30 minutes at RT)(Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM Citrate Buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes)Optimal dilution for a specific application should be determined.

    限制

    仅限研究用
  • 浓度

    200 μg/mL

    缓冲液

    10 mM PBS with 0.05 % BSA & 0.05 % azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-80 °C

    储存方法

    Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

    有效期

    24 months
  • 抗原

    Insulin (INS)

    别名

    INS

    分子量

    6kDa

    基因ID

    3630

    UniProt

    P01308

    途径

    NF-kappaB Signaling, RTK signaling, Positive Regulation of Peptide Hormone Secretion, Peptide Hormone Metabolism, Hormone Activity, Carbohydrate Homeostasis, ER-Nucleus Signaling, Regulation of Carbohydrate Metabolic Process, Feeding Behaviour, Autophagy, Negative Regulation of intrinsic apoptotic Signaling, Brown Fat Cell Differentiation, Positive Regulation of fat Cell Differentiation
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