CD137 抗体 (AA 19-188)
Quick Overview for CD137 抗体 (AA 19-188) (ABIN6939788)
抗原
See all CD137 (TNFRSF9) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 19-188
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纯化方法
- Purified by Protein A/G
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免疫原
- A recombinant fragment (around aa 19-188) of human CD137 / 4-1BB / TNFRSF9 protein (exact sequence is proprietary)
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亚型
- IgG1 kappa
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anti-Tumor Necrosis Factor Receptor Superfamily, Member 9 (TNFRSF9) (AA 101-200) antibody
TNFRSF9 适用: 人, 小鼠, 大鼠 ELISA, FACS, WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Tumor Necrosis Factor Receptor Superfamily, Member 9 (TNFRSF9) (AA 214-255) antibodyTNFRSF9 适用: 人 ELISA, FACS, WB 宿主: 小鼠 Monoclonal 2A12C2 unconjugated
anti-Tumor Necrosis Factor Receptor Superfamily, Member 9 (TNFRSF9) (AA 40-153) antibodyTNFRSF9 适用: 人 FACS, WB 宿主: 兔 Polyclonal unconjugated
anti-Tumor Necrosis Factor Receptor Superfamily, Member 9 (TNFRSF9) (AA 24-186) antibodyTNFRSF9 适用: 人 ELISA, FACS 宿主: 兔 Monoclonal DM66 unconjugated
anti-Tumor Necrosis Factor Receptor Superfamily, Member 9 (TNFRSF9) (AA 150-250) antibodyTNFRSF9 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Tumor Necrosis Factor Receptor Superfamily, Member 9 (TNFRSF9) (AA 24-186) antibodyTNFRSF9 适用: 人 ELISA, FACS 宿主: 小鼠 Monoclonal 4G10B9 unconjugated
anti-Tumor Necrosis Factor Receptor Superfamily, Member 9 (TNFRSF9) antibodyTNFRSF9 适用: 人, Non-Human Primate ELISA, FACS, IP 宿主: 小鼠 Monoclonal 4B4-1 unconjugated
anti-Tumor Necrosis Factor Receptor Superfamily, Member 9 (TNFRSF9) antibodyTNFRSF9 适用: 人, Non-Human Primate ELISA, FACS, Func, IP 宿主: 小鼠 Monoclonal 4B4-1 unconjugated
anti-Tumor Necrosis Factor Receptor Superfamily, Member 9 (TNFRSF9) (Internal Region) antibodyTNFRSF9 适用: 人, 大鼠 ELISA, WB, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Tumor Necrosis Factor Receptor Superfamily, Member 9 (TNFRSF9) antibodyTNFRSF9 适用: 人 FACS, WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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Positive Control: HEK293 cells, Jurkat whole cell lysate or recombinant human CD137 protein (WB). Human kidney cancer, liver, stomach or thyroid cancer tissue (IHC-P). Expressed on the surface of activated T- cells.
Known Application: ELISA (For coating, order antibody without BSA), Immunofluorescence (1-2 μg/mL), Flow Cytometry (1-2 μg/million cells), Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT),(Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 10-20 min followed by cooling at RT for 20 minutes),Optimal dilution for a specific application should be determined.
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限制
- 仅限研究用
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浓度
- 200 μg/mL
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缓冲液
- 10 mM PBS with 0.05 % BSA & 0.05 % azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-80 °C
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储存方法
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
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有效期
- 24 months
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- CD137 (TNFRSF9) (Tumor Necrosis Factor Receptor Superfamily, Member 9 (TNFRSF9))
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别名
- TNFRSF9
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背景
- CD137 belongs to the tumor necrosis factor receptor family and delivers a costimulatory signal to T lymphocytes. It is expressed on activated T cells and binds an inducible ligand that is found on B cells, macrophages and dendritic cells. Interactions between CD137 and its ligand are involved in antigen presentation and the generation of cytotoxic T cells. CD137 antibody may improve cancer treatment, and has been implicated in breast cancer, melanoma and lymphoma.
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分子量
- 32kDa (monomer), 85kDa (dimer)
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基因ID
- 3604
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UniProt
- Q07011
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途径
- Cancer Immune Checkpoints
抗原
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