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FLT3 抗体

FLT3 适用: 人 IHC, StM 宿主: 小鼠 Monoclonal FLT3-2458 unconjugated
产品编号 ABIN6935576
发货至: 中国
  • 抗原 See all FLT3 抗体
    FLT3 (Fms-Related tyrosine Kinase 3 (FLT3))
    适用
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    宿主
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    小鼠
    克隆类型
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    单克隆
    标记
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    This FLT3 antibody is un-conjugated
    应用范围
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    Immunohistochemistry (IHC), Staining Methods (StM)
    特异性
    Stem cell tyrosine kinase (STK-1) has been cloned from a CD34+ hematopoietic stem cell enriched library and identified as the human homolog of a previously identified gene of Mouse origin designated either Flk-2 or Flt-3. The STK-1 cDNA encodes a protein of 993 amino acids with 85 % identity to Flt-3/Flk-2. STK-1 is a member of the type III receptor tyrosine kinase family that includes Kit (steel factor receptor), Fms and PDGF. STK-1 expression in blood and marrow is restricted to CD34+ cells, a population greatly enriched for hematopoietic stem/progenitor cells. STK-1 antiserum recognizes two polypeptides in these cells. The Mouse homolog of STK-1, designated Flt-3/Flk-2, is expressed at high levels in hematopoietic cells and also in neural, gonadal, hepatic and placental tissues. It has been suggested that STK-1 and its murine homolog Flt-3/Flk-2 may function as growth factor receptors on hematopoietic stem and/or progenitor cells.
    纯化方法
    Purified by Protein A/G
    免疫原
    Recombinant full-length human FLT3 protein
    克隆位点
    FLT3-2458
    亚型
    IgG2b kappa
    Top Product
    Discover our top product FLT3 Primary Antibody
  • 应用备注

    Positive Control: Human lymph node or MDAMB468 xenograft.

    Known Application: Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT)(Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM Citrate Buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes)Optimal dilution for a specific application should be determined.

    限制
    仅限研究用
  • 浓度
    200 μg/mL
    缓冲液
    10 mM PBS with 0.05 % BSA & 0.05 % azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-80 °C
    储存方法
    Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
    有效期
    24 months
  • 抗原
    FLT3 (Fms-Related tyrosine Kinase 3 (FLT3))
    别名
    FLT3 (FLT3 产品)
    别名
    FLT3 antibody, B230315G04 antibody, CD135 antibody, Flk-2 antibody, Flk2 antibody, Flt-3 antibody, Ly72 antibody, wmfl antibody, FLK-2 antibody, FLK2 antibody, STK1 antibody, fms related tyrosine kinase 3 antibody, FMS-like tyrosine kinase 3 antibody, fms-related tyrosine kinase 3 antibody, FLT3 antibody, Flt3 antibody
    分子量
    160kDa
    基因ID
    2322
    UniProt
    P36888
    途径
    RTK signaling
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