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Recombinant CD21 抗体 (AA 44-196)

CR2 适用: 人 IHC, StM 宿主: 小鼠 Monoclonal rCR2-1952 unconjugated Recombinant Antibody
产品编号 ABIN6939181
发货至: 中国
  • 抗原 See all CD21 (CR2) 抗体
    CD21 (CR2) (Complement Component (3d/Epstein Barr Virus) Receptor 2 (CR2))
    抗体类型
    Recombinant Antibody
    抗原表位
    • 16
    • 16
    • 10
    • 7
    • 5
    • 4
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 44-196
    适用
    • 129
    • 27
    • 17
    • 16
    • 13
    • 11
    • 8
    • 8
    • 3
    • 2
    • 2
    • 1
    宿主
    • 82
    • 70
    • 1
    小鼠
    克隆类型
    • 93
    • 59
    • 1
    单克隆
    标记
    • 68
    • 20
    • 15
    • 14
    • 7
    • 5
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This CD21 antibody is un-conjugated
    应用范围
    • 105
    • 64
    • 48
    • 40
    • 27
    • 27
    • 24
    • 16
    • 15
    • 6
    • 6
    • 6
    • 5
    • 1
    • 1
    • 1
    Immunohistochemistry (IHC), Staining Methods (StM)
    特异性
    Recognizes a protein of 140 kDa, which is identified as the complement receptor 2(CR2)/CD21. This protein is expressed strongly on mature B cells, follicular dendritic cells and weakly on immature thymocytes and T lymphocytes. In B-cell ontogeny, CD21 appears after the pre-B-stage, is maintained during peripheral B-cell development and is lost upon terminal differentiation into plasma cells. CD21 expression is also gradually lost after stimulation of B cells in vitro.CD21 functions as receptor for C3d, C3dg and iC3b Complement components, for EBV and for IFNalpha.CD21 binds to CD23 and associates with CD19, CD81 and Leu13 to form a large signal-transduction complex involved in B cell activation.
    纯化方法
    Purified by Protein A/G
    免疫原
    Recombinant fragment (around aa 44-196) of human CR2 (CD21) protein (exact sequence is proprietary)
    克隆位点
    RCR2-1952
    亚型
    IgG1 kappa
    Top Product
    Discover our top product CR2 Primary Antibody
  • 应用备注

    Positive Control: WEHI-231 cells. Human tonsil (IHC).

    Known Application: Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 min at RT),(Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM Citrate Buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes),Optimal dilution for a specific application should be determined.

    限制
    仅限研究用
  • 浓度
    200 μg/mL
    缓冲液
    10 mM PBS with0.05 % BSA & 0.05 % azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-80 °C
    储存方法
    Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
    有效期
    24 months
  • 抗原
    CD21 (CR2) (Complement Component (3d/Epstein Barr Virus) Receptor 2 (CR2))
    别名
    CR2 (CR2 产品)
    别名
    C3DR antibody, CD21 antibody, CR antibody, CVID7 antibody, SLEB9 antibody, Cd21 antibody, cd21 antibody, CR1 antibody, CR1-L antibody, CR2 antibody, complement C3d receptor 2 antibody, complement C3b/C4b receptor 1 (Knops blood group) antibody, CR2 antibody, Cr2 antibody, CR1 antibody
    分子量
    140kDa
    基因ID
    1380
    UniProt
    P20023
    途径
    Complement System
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