SDHB 抗体 (AA 165-273)
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- 抗原 See all SDHB 抗体
- SDHB (Succinate Dehydrogenase Complex, Subunit B, Iron Sulfur (Ip) (SDHB))
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抗原表位
- AA 165-273
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This SDHB antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 特异性
- Succinate dehydrogenase (SDH) is Complex II in the mitochondria, vital for mitochondrial electron transport, as well as Krebs cycle function.Four subunits comprise the SDH protein complex: a flavochrome subunit (SDHA), an iron-sulfur protein (SDHB) and two membrane-bound subunits (SDHC and SDHD) anchored to the inner mitochondrial membrane. The SDH complex functions as a tumor suppressor. Loss of any subunit proteins lead to destabilization of the complex and tumor formation.Antibody to SDHB is helpful in the identification of phaeochromocytomas, paragangliomas and GIST.
- 交叉反应 (详细)
- Human.
- 纯化方法
- 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
- 免疫原
- Recombinant fragment (around aa 165-273) of human SDHB protein (exact sequence is proprietary)
- 克隆位点
- SDHB-2382
- 亚型
- IgG2b kappa
- Top Product
- Discover our top product SDHB Primary Antibody
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- 应用备注
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Known_Application: Western Blot (1-2 μg/mL), Optimal dilution for a specific application should be determined.
Positive_Control: Jurkat or HepG2 cells. Human kidney or liver.
- 限制
- 仅限研究用
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- 浓度
- 1.0 mg/mL
- 缓冲液
- Prepared in 10 mM PBS, WITHOUT BSA and Azide.
- 储存液
- Azide free
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
- 有效期
- 24 months
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- 抗原
- SDHB (Succinate Dehydrogenase Complex, Subunit B, Iron Sulfur (Ip) (SDHB))
- 别名
- SDHB (SDHB 产品)
- 别名
- succinate dehydrogenase 2-3 antibody, CG3283 antibody, Dmel\\CG3283 antibody, Ip antibody, SDH antibody, SDH-IP antibody, SDH-Ip antibody, SDHb antibody, sdhB antibody, CWS2 antibody, IP antibody, PGL4 antibody, SDH1 antibody, SDH2 antibody, SDHIP antibody, 0710008N11Rik antibody, fj46d06 antibody, wu:fj46d06 antibody, succinate dehydrogenase complex iron sulfur subunit B antibody, succinate dehydrogenase [ubiquinone] iron-sulfur subunit 3 antibody, Succinate dehydrogenase, subunit B (iron-sulfur) antibody, succinate dehydrogenase complex subunit B, iron sulfur (Ip) antibody, succinate dehydrogenase complex, subunit B, iron sulfur (Ip) antibody, succinate dehydrogenase complex subunit B, iron sulfur (Ip) S homeolog antibody, SDHB antibody, SDH2-3 antibody, SdhB antibody, sdhb antibody, Sdhb antibody, sdhb.S antibody
- 背景
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CWS2, DHSB, Iron-sulfur subunit of complex II, PGL4, SDH2, SDHB, SDHIP, Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial, Succinate Dehydrogenase Complex Subunit B Iron Sulfur Protein,SDHB (Succinate Dehydrogenase B) (Pheochromocytoma Marker)
Cellular localisation: Cytoplasmic (Mitochondria) - 分子量
- 32kDa
- 基因ID
- 6390, 465924
- UniProt
- P21912
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