SDHB 抗体 (AA 29-280)
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北京 101111
Quick Overview for SDHB 抗体 (AA 29-280) (ABIN7193552)
抗原
See all SDHB 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 29-280
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原理
- SDHB Antibody
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纯化方法
- Purified antibody
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免疫原
- Purified recombinant fragment of human SDHB (AA: 29-280) expressed in E. Coli.
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亚型
- IgG1
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应用备注
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ELISA: 1/10000
FCM: 1/200 - 1/400
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Purified antibody in PBS with 0.05 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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- SDHB (Succinate Dehydrogenase Complex, Subunit B, Iron Sulfur (Ip) (SDHB))
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别名
- SDHB
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背景
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Complex II of the respiratory chain, which is specifically involved in the oxidation of succinate, carries electrons from FADH to CoQ. The complex is composed of four nuclear-encoded subunits and is localized in the mitochondrial inner membrane. The iron-sulfur subunit is highly conserved and contains three cysteine-rich clusters which may comprise the iron-sulfur centers of the enzyme. Sporadic and familial mutations in this gene result in paragangliomas and pheochromocytoma, and support a link between mitochondrial dysfunction and tumorigenesis.
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分子量
- 31.6 kDa
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UniProt
- P21912
抗原
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