MAGEA1 抗体
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- 抗原 See all MAGEA1 抗体
- MAGEA1 (Melanoma Antigen Family A, 1 (Directs Expression of Antigen MZ2-E) (MAGEA1))
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This MAGEA1 antibody is un-conjugated
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应用范围
- Immunohistochemistry (Formalin-fixed Sections) (IHC (f))
- 特异性
- Recognizes a protein of 42-46kDa, identified as MAGE-1. This MAb does not cross-react with MAGE-2, -3, -4, -6 -9, -10, -or -12 protein. Human malignant neoplasms carry rejection antigens that are recognized by the patients' autologous, tumor directed and specific, cytolytic, CD8+ T lymphocyte clones (CTL). The MAGE family of genes codes an important group of antigens. It was identified that melanomas and primary glial brain tumors express common melanoma associated antigens (MAAs). Because MAGE-1 is expressed on a significant proportion of human neoplasms of various histological types (melanoma, brain tumors of glial origin, neuroblastoma, non-small cell lung cancer, breast, gastric, colorectal, ovarian, renal cell carcinomas) and not on normal tissues, the encoded antigen may serve as a marker of early detection and target for cancer immunotherapy.
- 交叉反应 （详细）
- Human. Rat. Dog.
- 纯化方法
- 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
- 免疫原
- Recombinant full-length human MAGE-A1 protein
- 克隆位点
- MA454
- 亚型
- IgG1 kappa
- Top Product
- Discover our top product MAGEA1 Primary Antibody
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anti-Melanoma Antigen Family A, 1 (Directs Expression of Antigen MZ2-E) (MAGEA1) (AA 1-309) antibody
MAGEA1 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Melanoma Antigen Family A, 1 (Directs Expression of Antigen MZ2-E) (MAGEA1) (C-Term) antibodyMAGEA1 适用: 人, 大鼠, 小鼠 WB, IHC, IF, ELISA, ICC 宿主: 兔 Polyclonal unconjugated
anti-Melanoma Antigen Family A, 1 (Directs Expression of Antigen MZ2-E) (MAGEA1) (AA 1-309) antibodyMAGEA1 适用: 人 IHC, ELISA, IP 宿主: 兔 Polyclonal unconjugated
anti-Melanoma Antigen Family A, 1 (Directs Expression of Antigen MZ2-E) (MAGEA1) (AA 2-225) antibodyMAGEA1 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Melanoma Antigen Family A, 1 (Directs Expression of Antigen MZ2-E) (MAGEA1) (AA 38-87) antibodyMAGEA1 适用: 人 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Melanoma Antigen Family A, 1 (Directs Expression of Antigen MZ2-E) (MAGEA1) (AA 101-200) antibodyMAGEA1 适用: 人, 大鼠 WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Melanoma Antigen Family A, 1 (Directs Expression of Antigen MZ2-E) (MAGEA1) antibodyMAGEA1 适用: 人 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Melanoma Antigen Family A, 1 (Directs Expression of Antigen MZ2-E) (MAGEA1) antibodyMAGEA1 适用: 人, 大鼠, 犬 IHC, StM 宿主: 小鼠 Monoclonal MA454 unconjugated
anti-Melanoma Antigen Family A, 1 (Directs Expression of Antigen MZ2-E) (MAGEA1) (AA 98-171) antibodyMAGEA1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 3H5 unconjugated
anti-Melanoma Antigen Family A, 1 (Directs Expression of Antigen MZ2-E) (MAGEA1) (N-Term) antibodyMAGEA1 适用: 人, 小鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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Known_Application: Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT)(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes), Optimal dilution for a specific application should be determined.
Positive_Control: Melanoma cell lines. Melanomas or testicular carcinomas.
- 限制
- 仅限研究用
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- 浓度
- 1.0 mg/mL
- 缓冲液
- Prepared in 10 mM PBS, WITHOUT BSA and Azide.
- 储存液
- Azide free
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
- 有效期
- 24 months
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- 抗原
- MAGEA1 (Melanoma Antigen Family A, 1 (Directs Expression of Antigen MZ2-E) (MAGEA1))
- 别名
- MAGEA1 (MAGEA1 产品)
- 别名
- CT1.1 antibody, MAGE1 antibody, Mage-a1 antibody, MAGE family member A1 antibody, melanoma antigen, family A, 1 antibody, MAGEA1 antibody, Magea1 antibody
- 背景
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MZ2 E, cancer/testis antigen 1.1, CT1.1, MAGE1A, MAGEA1, Melanoma antigen family A 1, Melanoma associated antigen 1, Melanoma associated antigen MZ2 E,MAGE-1 (Target for Cancer Immunotherapy)
Cellular localisation: Cytoplasmic - 分子量
- 42-46kDa
- 基因ID
- 4100, 72879
- UniProt
- P43355
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