-
- 抗原 See all MAGEA1 抗体
- MAGEA1 (Melanoma Antigen Family A, 1 (Directs Expression of Antigen MZ2-E) (MAGEA1))
-
适用
- 人, 大鼠, 犬
-
宿主
- 小鼠
-
克隆类型
- 单克隆
-
标记
- This MAGEA1 antibody is un-conjugated
-
应用范围
- Immunohistochemistry (IHC), Staining Methods (StM)
- 特异性
- Recognizes a protein of 42-46 kDa, identified as MAGE-1. This MAb does not cross-react with MAGE-2, -3, -4, -6 -9, -10, -or -12 protein. Human malignant neoplasms carry rejection antigens that are recognized by the patients' autologous, tumor directed and specific, cytolytic, CD8+ T lymphocyte clones (CTL). The MAGE family of genes codes an important group of antigens. It was identified that melanomas and primary glial brain tumors express common melanoma associated antigens (MAAs). Because MAGE-1 is expressed on a significant proportion of human neoplasms of various histological types (melanoma, brain tumors of glial origin, neuroblastoma, non-small cell lung cancer, breast, gastric, colorectal, ovarian, renal cell carcinomas) and not on normal tissues, the encoded antigen may serve as a marker of early detection and target for cancer immunotherapy.
- 纯化方法
- Purified by Protein A/G
- 免疫原
- Recombinant full-length human MAGE-A1 protein
- 克隆位点
- MA454
- 亚型
- IgG1 kappa
- Top Product
- Discover our top product MAGEA1 Primary Antibody
-
anti-Melanoma Antigen Family A, 1 (Directs Expression of Antigen MZ2-E) (MAGEA1) (AA 1-309) antibody
MAGEA1 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Melanoma Antigen Family A, 1 (Directs Expression of Antigen MZ2-E) (MAGEA1) (C-Term) antibodyMAGEA1 适用: 人, 大鼠, 小鼠 WB, IHC, IF, ELISA, ICC 宿主: 兔 Polyclonal unconjugated
anti-Melanoma Antigen Family A, 1 (Directs Expression of Antigen MZ2-E) (MAGEA1) (AA 1-309) antibodyMAGEA1 适用: 人 IHC, ELISA, IP 宿主: 兔 Polyclonal unconjugated
anti-Melanoma Antigen Family A, 1 (Directs Expression of Antigen MZ2-E) (MAGEA1) (AA 2-225) antibodyMAGEA1 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Melanoma Antigen Family A, 1 (Directs Expression of Antigen MZ2-E) (MAGEA1) (AA 38-87) antibodyMAGEA1 适用: 人 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Melanoma Antigen Family A, 1 (Directs Expression of Antigen MZ2-E) (MAGEA1) (AA 101-200) antibodyMAGEA1 适用: 人, 大鼠 WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Melanoma Antigen Family A, 1 (Directs Expression of Antigen MZ2-E) (MAGEA1) antibodyMAGEA1 适用: 人 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Melanoma Antigen Family A, 1 (Directs Expression of Antigen MZ2-E) (MAGEA1) (AA 98-171) antibodyMAGEA1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 3H5 unconjugated
anti-Melanoma Antigen Family A, 1 (Directs Expression of Antigen MZ2-E) (MAGEA1) (N-Term) antibodyMAGEA1 适用: 人, 小鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Melanoma Antigen Family A, 1 (Directs Expression of Antigen MZ2-E) (MAGEA1) (AA 143-173) antibodyMAGEA1 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB2081-2082 unconjugated
-
- 应用备注
-
Positive Control: Melanoma cell lines. Melanomas or testicular carcinomas.
Known Application: Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT)(Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes)Optimal dilution for a specific application should be determined.
- 限制
- 仅限研究用
-
- 浓度
- 200 μg/mL
- 缓冲液
- 10 mM PBS with 0.05 % BSA & 0.05 % azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-80 °C
- 储存方法
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
- 有效期
- 24 months
-
- 抗原
- MAGEA1 (Melanoma Antigen Family A, 1 (Directs Expression of Antigen MZ2-E) (MAGEA1))
- 别名
- MAGEA1 (MAGEA1 产品)
- 别名
- CT1.1 antibody, MAGE1 antibody, Mage-a1 antibody, MAGE family member A1 antibody, melanoma antigen, family A, 1 antibody, MAGEA1 antibody, Magea1 antibody
- 分子量
- 42-46kDa
- 基因ID
- 4100
- UniProt
- P43355
-
You are here:
