CD11c 抗体 (AA 637-827)
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- 抗原 See all CD11c (ITGAX) 抗体
- CD11c (ITGAX) (Integrin, alpha X (Complement Component 3 Receptor 4 Subunit) (ITGAX))
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抗原表位
- AA 637-827
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This CD11c antibody is un-conjugated
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应用范围
- Immunohistochemistry (Formalin-fixed Sections) (IHC (f))
- 特异性
- Recognizes a protein of 145 kDa, identified as CD11c. CD11c (ITGAX), a member of the leukointegrin family, shares the same beta subunit with other members of the leukocyte adhesion molecule family, which includes CD11a (LFA-1), CD11b (MAC-1) and CD11d (ITGAD), but has a unique alpha chain. CD11c has been shown to play a role in phagocytosis, cell migration, and cytokine production by monocytes/macrophages as well as induction of T-cell proliferation by Langerhans cells. CD11c is expressed prominently on the plasma membranes of monocytes, tissue macrophages, NK cells, and most dendritic cells (DCs). A lower level of expression is also observed on neutrophils as a result of its high level of expression on most DCs. An antibody to CD11c may aid in identification of lesions with histiocytic origin. It may also been used as a marker for hairy cell leukemia in paraffin-embedded tissues.
- 交叉反应 （详细）
- Human.
- 纯化方法
- 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
- 免疫原
- Recombinant human ITGAX protein fragment (aa 637-827) (exact sequence is proprietary)
- 克隆位点
- ITGAX-1242
- 亚型
- IgG2b kappa
- Top Product
- Discover our top product ITGAX Primary Antibody
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anti-Integrin, alpha X (Complement Component 3 Receptor 4 Subunit) (ITGAX) antibody
ITGAX 适用: 人, 小鼠, 大鼠 IHC, WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Integrin, alpha X (Complement Component 3 Receptor 4 Subunit) (ITGAX) antibody (FITC)ITGAX 适用: 人, 猴 FACS 宿主: 小鼠 Monoclonal BU15 FITC
anti-Integrin, alpha X (Complement Component 3 Receptor 4 Subunit) (ITGAX) (AA 1119-1145) antibodyITGAX 适用: 人 FACS, IHC, WB, IF, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Integrin, alpha X (Complement Component 3 Receptor 4 Subunit) (ITGAX) (AA 100-350) antibodyITGAX 适用: 人 IHC, WB, IF, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Integrin, alpha X (Complement Component 3 Receptor 4 Subunit) (ITGAX) antibodyITGAX 适用: 人, 小鼠, 大鼠 IHC 宿主: 兔 Polyclonal unconjugated
anti-Integrin, alpha X (Complement Component 3 Receptor 4 Subunit) (ITGAX) antibodyITGAX 适用: 人, 猴 FACS, IP, IHC (fro) 宿主: 小鼠 Monoclonal BU15 unconjugated
anti-Integrin, alpha X (Complement Component 3 Receptor 4 Subunit) (ITGAX) (AA 102-279) antibodyITGAX 适用: 人 FACS, IHC, WB, ELISA, ICC, Neut 宿主: 小鼠 Monoclonal 6G2D1 unconjugated
anti-Integrin, alpha X (Complement Component 3 Receptor 4 Subunit) (ITGAX) (AA 1119-1145), (C-Term) antibodyITGAX 适用: 人 FACS, WB, IF, IHC (p) 宿主: 兔 Polyclonal RB21771 unconjugated
anti-Integrin, alpha X (Complement Component 3 Receptor 4 Subunit) (ITGAX) (AA 637-827) antibodyITGAX 适用: 人 IHC, StM 宿主: 小鼠 Monoclonal ITGAX-1242 unconjugated
anti-Integrin, alpha X (Complement Component 3 Receptor 4 Subunit) (ITGAX) (N-Term) antibodyITGAX 适用: 人, 小鼠 IHC, WB, IF, ELISA, ICC 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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Known_Application: Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT)(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes), Optimal dilution for a specific application should be determined.
Positive_Control: THP-1 cells. Tonsil or Lymph Node.
- 限制
- 仅限研究用
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- 浓度
- 1.0 mg/mL
- 缓冲液
- Prepared in 10 mM PBS, WITHOUT BSA and Azide.
- 储存液
- Azide free
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
- 有效期
- 24 months
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- 抗原
- CD11c (ITGAX) (Integrin, alpha X (Complement Component 3 Receptor 4 Subunit) (ITGAX))
- 别名
- ITGAX (ITGAX 产品)
- 别名
- CD11C antibody, SLEB6 antibody, RGD1561123 antibody, AI449405 antibody, Cd11c antibody, Cr4 antibody, N418 antibody, integrin subunit alpha X antibody, integrin alpha X antibody, ITGAX antibody, Itgax antibody
- 背景
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CD11 antigen-like family member C, Complement component 3 receptor 4 subunit, Integrin alpha-X, integrin, alpha X (antigen CD11C (p150), alpha polypeptide), Leu M5 alpha subunit, Leukocyte adhesion glycoprotein p150 95 alpha chain, Myeloid membrane antigen alpha subunit, p150/95,CD11c (Dendritic Cell Marker)
Cellular localisation: Cell Surface - 分子量
- 145kDa
- 基因ID
- 3687, 248472
- UniProt
- P20702
- 途径
- Complement System, Activated T Cell Proliferation, Integrin Complex
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