FCER2 抗体 (AA 48-321)
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- 抗原 See all FCER2 抗体
- FCER2 (Fc Fragment of IgE, Low Affinity II, Receptor For (CD23) (FCER2))
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抗原表位
- AA 48-321
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This FCER2 antibody is un-conjugated
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应用范围
- Immunohistochemistry (IHC), Immunohistochemistry (Formalin-fixed Sections) (IHC (f))
- 特异性
- CD23 (FCE2) is a type II integral membrane glycoprotein that is expressed on mature B cells, monocytes, eosinophils, platelets and dendritic cells. CD23 is a low affinity IgE receptor that mediates IgE-dependent cytotoxicity and phagocytosis by macrophages and eosinophils. CD23 associates as an oligomer where cooperative binding of at least two lectin domains is required for high affinity IgE binding to CD23. It may play a role in antigen presentation by B cells by interacting with CD40. CD23 has been shown to be associated with the Fyn tyrosine kinase. The truncated molecule can be secreted, then function as a potent mitogenic growth factor. CD23 is expressed on a subpopulation of peripheral blood cells, B-lymphocytes and on EBV transformed B lymphoblastoid cell lines. CD23 is also detected in neoplastic cells from cases of B cell chronic lymphocytic leukemia and some cases on centroblastic/centrocytic lymphoma.
- 交叉反应 （详细）
- Human.
- 纯化方法
- 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
- 免疫原
- Recombinant fragment (around aa 48-321) of human FCER2/CD23 protein (exact sequence is proprietary)
- 克隆位点
- FCER2-3592
- 亚型
- IgG2b kappa
- Top Product
- Discover our top product FCER2 Primary Antibody
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anti-Fc Fragment of IgE, Low Affinity II, Receptor For (CD23) (FCER2) antibody
FCER2 适用: 人 WB, IHC, IF 宿主: 兔 Monoclonal unconjugated
anti-Fc Fragment of IgE, Low Affinity II, Receptor For (CD23) (FCER2) (AA 151-321) antibodyFCER2 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Fc Fragment of IgE, Low Affinity II, Receptor For (CD23) (FCER2) (AA 150-330) antibodyFCER2 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Fc Fragment of IgE, Low Affinity II, Receptor For (CD23) (FCER2) antibodyFCER2 适用: 人, 小鼠, 大鼠 IF, IHC (p) 宿主: 小鼠 Monoclonal 2F2 unconjugated
anti-Fc Fragment of IgE, Low Affinity II, Receptor For (CD23) (FCER2) (AA 48-321) antibodyFCER2 适用: 人 IHC, StM 宿主: 小鼠 Monoclonal FCER2-3592 unconjugated
anti-Fc Fragment of IgE, Low Affinity II, Receptor For (CD23) (FCER2) (AA 1-321) antibodyFCER2 适用: 人 WB, ELISA, IP 宿主: 小鼠 Monoclonal S52 unconjugated
anti-Fc Fragment of IgE, Low Affinity II, Receptor For (CD23) (FCER2) (AA 1-321) antibodyFCER2 适用: 人 WB, ELISA, IP 宿主: 小鼠 Monoclonal S51 unconjugated
anti-Fc Fragment of IgE, Low Affinity II, Receptor For (CD23) (FCER2) (AA 1-321) antibodyFCER2 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 2A7 unconjugated
anti-Fc Fragment of IgE, Low Affinity II, Receptor For (CD23) (FCER2) (AA 48-321) antibodyFCER2 适用: 人 WB, IHC, IHC (p) 宿主: 小鼠 Monoclonal 2B6 unconjugated
anti-Fc Fragment of IgE, Low Affinity II, Receptor For (CD23) (FCER2) (AA 48-321) antibodyFCER2 适用: 人 IHC 宿主: 小鼠 Monoclonal MSVA-023M unconjugated
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- 应用备注
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Known_Application: Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT),(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95 °C followed by cooling at RT for 20 minutes),Optimal dilution for a specific application should be determined.
Positive_Control: Human lymph node or tonsil (IHC).
- 限制
- 仅限研究用
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- 浓度
- 1.0 mg/mL
- 缓冲液
- Prepared in 10 mM PBS, WITHOUT BSA and Azide.
- 储存液
- Azide free
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
- 有效期
- 24 months
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- 抗原
- FCER2 (Fc Fragment of IgE, Low Affinity II, Receptor For (CD23) (FCER2))
- 别名
- FCER2 (FCER2 产品)
- 别名
- BLAST-2 antibody, CD23 antibody, CD23A antibody, CLEC4J antibody, FCE2 antibody, IGEBF antibody, Fcer2a antibody, Fc fragment of IgE receptor II antibody, FCER2 antibody, Fcer2 antibody
- 背景
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BLAST-2, C-type lectin domain family 4, member J, Fc fragment of IgE low affinity II receptor, Fc-epsilon-RII, FCER2, FCER2A, FceRII, IgE-binding factor (IGEBF), Immunoglobulin E receptor, low affinity II, Lymphocyte IgE receptor,CD23 (Fc Epsilon RII)
Cellular localisation: Cell Surface - 分子量
- 37kDa (soluble form), 45kDa (membrane-bound form)
- 基因ID
- 2208, 465778
- UniProt
- P06734
- 途径
- Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process
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