FCER2 抗体 (AA 48-321)
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Quick Overview for FCER2 抗体 (AA 48-321) (ABIN6939372)
抗原
See all FCER2 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 48-321
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纯化方法
- Purified by Protein A/G
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免疫原
- Recombinant fragment (around aa 48-321) of human FCER2/CD23 protein (exact sequence is proprietary)
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亚型
- IgG2b kappa
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anti-Fc Fragment of IgE, Low Affinity II, Receptor For (CD23) (FCER2) (AA 151-321) antibody
FCER2 适用: 人 IHC, WB 宿主: 兔 Polyclonal unconjugated
anti-Fc Fragment of IgE, Low Affinity II, Receptor For (CD23) (FCER2) (AA 150-330) antibodyFCER2 适用: 小鼠 IHC, WB, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Fc Fragment of IgE, Low Affinity II, Receptor For (CD23) (FCER2) (AA 48-321) antibodyFCER2 适用: 人 IHC 宿主: 小鼠 Monoclonal 023M unconjugated
anti-Fc Fragment of IgE, Low Affinity II, Receptor For (CD23) (FCER2) (AA 1-321) antibodyFCER2 适用: 人 WB, ELISA, IP 宿主: 小鼠 Monoclonal S51 unconjugated
anti-Fc Fragment of IgE, Low Affinity II, Receptor For (CD23) (FCER2) (AA 1-321) antibodyFCER2 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 2A7 unconjugated
anti-Fc Fragment of IgE, Low Affinity II, Receptor For (CD23) (FCER2) (AA 1-321) antibodyFCER2 适用: 人 WB, ELISA, IP 宿主: 小鼠 Monoclonal S52 unconjugated
anti-Fc Fragment of IgE, Low Affinity II, Receptor For (CD23) (FCER2) (AA 50-331) antibodyFCER2 适用: 人, 小鼠, 大鼠 FACS, IHC, WB, ELISA, ICC, IF, IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Fc Fragment of IgE, Low Affinity II, Receptor For (CD23) (FCER2) (AA 48-321) antibodyFCER2 适用: 人 IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Fc Fragment of IgE, Low Affinity II, Receptor For (CD23) (FCER2) (C-Term) antibodyFCER2 适用: 人, 小鼠, 大鼠 IHC, WB, ELISA, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-Fc Fragment of IgE, Low Affinity II, Receptor For (CD23) (FCER2) antibody (FITC)FCER2 适用: 人 FACS, IHC, IHC (fro) 宿主: 小鼠 Monoclonal EBVCS2 FITC
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应用备注
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Positive Control: Human lymph node or tonsil (IHC).
Known Application: Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT),(Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes),Optimal dilution for a specific application should be determined.
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限制
- 仅限研究用
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浓度
- 200 μg/mL
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缓冲液
- 10 mM PBS with 0.05 % BSA & 0.05 % azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-80 °C
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储存方法
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
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有效期
- 24 months
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- FCER2 (Fc Fragment of IgE, Low Affinity II, Receptor For (CD23) (FCER2))
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别名
- FCER2
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背景
- CD23 (FCE2) is a type II integral membrane glycoprotein that is expressed on mature B cells, monocytes, eosinophils, platelets and dendritic cells. CD23 is a low affinity IgE receptor that mediates IgE-dependent cytotoxicity and phagocytosis by macrophages and eosinophils. CD23 associates as an oligomer where cooperative binding of at least two lectin domains is required for high affinity IgE binding to CD23. It may play a role in antigen presentation by B cells by interacting with CD40. CD23 has been shown to be associated with the Fyn tyrosine kinase. The truncated molecule can be secreted, then function as a potent mitogenic growth factor. CD23 is expressed on a subpopulation of peripheral blood cells, B-lymphocytes and on EBV transformed B lymphoblastoid cell lines. CD23 is also detected in neoplastic cells from cases of B cell chronic lymphocytic leukemia and some cases on centroblastic/centrocytic lymphoma.
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分子量
- 37kDa (soluble form), 45kDa (membrane-bound form)
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基因ID
- 2208
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UniProt
- P06734
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途径
- Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process
抗原
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