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FCER2 抗体 (AA 50-331)

FCER2 适用: 人, 小鼠, 大鼠 WB, IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN3043829
发货至: 中国
  • 抗原 See all FCER2 抗体
    FCER2 (Fc Fragment of IgE, Low Affinity II, Receptor For (CD23) (FCER2))
    抗原表位
    • 17
    • 13
    • 7
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 50-331
    适用
    人, 小鼠, 大鼠
    宿主
    • 57
    • 46
    • 16
    克隆类型
    • 76
    • 41
    • 2
    多克隆
    标记
    • 56
    • 16
    • 10
    • 8
    • 5
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This FCER2 antibody is un-conjugated
    应用范围
    • 72
    • 51
    • 33
    • 20
    • 13
    • 10
    • 9
    • 7
    • 5
    • 5
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
    原理
    Rabbit IgG polyclonal antibody for Low affinity immunoglobulin epsilon Fc receptor(FCER2) detection. Tested with WB, IHC-P in Human,Mouse,Rat.
    交叉反应 (详细)
    No cross reactivity with other proteins.
    产品特性
    Rabbit IgG polyclonal antibody for Low affinity immunoglobulin epsilon Fc receptor(FCER2) detection. Tested with WB, IHC-P in Human,Mouse,Rat.
    Gene Name: Fc fragment of IgE, low affinity II, receptor for (CD23)
    Protein Name: Low affinity immunoglobulin epsilon Fc receptor
    纯化方法
    Immunogen affinity purified.
    免疫原
    E.coli-derived mouse CD23 recombinant protein (Position: E50-P331). Mouse CD23 shares 52% amino acid (aa) sequence identity with human CD23.
    亚型
    IgG
    Top Product
    Discover our top product FCER2 Primary Antibody
  • 应用备注
    WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Mouse, The detection limit for CD23 is approximately 0.25 ng/lane under reducing conditions.
    IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Human, Mouse, Rat, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
    IHC-F: Concentration: 0.5-1 μg/mL, Tested Species: Mouse
    Notes: Tested Species: Species with positive results. Other applications have not been tested. Optimal dilutions should be determined by end users.
    说明

    Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P) and IHC(F).

    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
    浓度
    500 μg/mL
    缓冲液
    Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    At -20°C for one year. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
  • 抗原
    FCER2 (Fc Fragment of IgE, Low Affinity II, Receptor For (CD23) (FCER2))
    别名
    FCER2 (FCER2 产品)
    别名
    BLAST-2 antibody, CD23 antibody, CD23A antibody, CLEC4J antibody, FCE2 antibody, IGEBF antibody, Fcer2a antibody, Fc fragment of IgE receptor II antibody, FCER2 antibody, Fcer2 antibody
    背景
    CD23, also known as Fc epsilon RII, or FcεRII, is the "low-affinity" receptor for IgE, an antibody isotype involved in allergy and resistance to parasites, and is important in regulation of IgE levels. There are two forms of CD23: CD23a and CD23b. CD23a is present on follicular B cells, whereas CD23b requires IL-4 to be expressed on T-cells, monocytes, Langerhans cells, eosinophils, and macrophages. As part of a mapping of multiple probes to specific bands on chromosome 19 by fluorescence in situ hybridization, the FCE2 gene was assigned to 19p13.3. CD23 (FCE2) is a key molecule for B-cell activation and growth. It is the low-affinity receptor for IgE. The truncated molecule can be secreted, then functioning as a potent mitogenic growth factor.

    Synonyms: Blast 2 antibody|BLAST-2 antibody|Blast2 antibody|C type lectin domain family 4 member J antibody|C-type lectin domain family 4 member J antibody|C-type lectin domain family 4, member J antibody|CD 23 antibody|CD 23A antibody|CD23 antibody|CD23 antigen antibody|CD23A antibody|CLEC 4J antibody|CLEC4J antibody|Fc epsilon RII antibody|Fc fragment of IgE low affinity II receptor for antibody|Fc fragment of IgE, low affinity II, receptor for (CD23) antibody|Fc of IgE, low affinity II, receptor for (CD23) antibody|Fc receptor IgE low affinity II alpha polypeptide antibody|Fc receptor, IgE, low affinity II, alpha polypeptide, isoform CRA_a antibody|Fc-epsilon-RII antibody|FCE 2 antibody|FCE2 antibody|FCER 2 antibody|Fcer2 antibody|FCER2_HUMAN antibody|FCER2A antibody|FceRII antibody|IgE binding factor antibody|IgE receptor lymphocyte antibody|IgE-binding factor antibody|IGEBF antibody|Immunoglobulin E binding factor antibody|Immunoglobulin E receptor, low affinity II antibody|Immunoglobulin E-binding factor antibody|LEUKOCYTE ANTIGEN CD23 antibody|Low Affinity IgE Receptor antibody|Low affinity immunoglobulin epsilon Fc receptor antibody|Low affinity immunoglobulin epsilon Fc receptor membrane bound form antibody|Low affinity immunoglobulin epsilon Fc receptor soluble form antibody|Ly-42 antibody|Ly42 antibody|Lymphocyte antigen CD23 antibody|Lymphocyte IgE receptor antibody|MGC93219 antibody
    基因ID
    14128
    UniProt
    P20693
    途径
    Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process
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