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FCER2 抗体 (AA 50-331)

The 兔 多克隆 anti-FCER2 antibody is suitable to detect FCER2 in samples from 人, 小鼠 和 大鼠. It has been validated for FACS, IHC, WB, ELISA, ICC, IF 和 IHC (fro).
产品编号 ABIN3043829
发货至: 中国
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Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for FCER2 抗体 (AA 50-331) (ABIN3043829)

抗原

See all FCER2 抗体
FCER2 (Fc Fragment of IgE, Low Affinity II, Receptor For (CD23) (FCER2))

适用

人, 小鼠, 大鼠

宿主

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克隆类型

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多克隆

标记

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This FCER2 antibody is un-conjugated

应用范围

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Flow Cytometry (FACS), Immunohistochemistry (IHC), Western Blotting (WB), ELISA, Immunocytochemistry (ICC), Immunofluorescence (IF), Immunohistochemistry (Frozen Sections) (IHC (fro))
  • 抗原表位

    • 27
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    AA 50-331

    原理

    Anti-CD23/FCER2 Antibody

    交叉反应 (详细)

    No cross-reactivity with other proteins

    产品特性

    Anti-CD23/FCER2 Antibody (ABIN3043829). Tested in ELISA, Flow Cytometry, IF, IHC, IHC-F, ICC, WB applications. This antibody reacts with Human, Mouse, Rat. This is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications.

    纯化方法

    Immunogen affinity purified.

    免疫原

    E.coli-derived mouse CD23 recombinant protein (Position: E50-P331). Mouse CD23 shares 52% amino acid (aa) sequence identity with human CD23.

    亚型

    IgG
  • 应用备注

    Western blot, 0.1-0.5 μg/mL, Mouse, Rat
    Immunohistochemistry (Frozen Section), 0.5-1 μg/mL, Mouse
    Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL, Human, Mouse, Rat
    Immunocytochemistry, 0.5-1 μg/mL, Human
    Immunofluorescence, 2 μg/mL, Mouse, Rat
    Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Mouse
    ELISA (Cap), 1-5 μg/mL, Mouse

    说明

    Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P) and IHC(F).

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    浓度

    500 μg/mL

    缓冲液

    Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg NaN3.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
  • 抗原

    FCER2 (Fc Fragment of IgE, Low Affinity II, Receptor For (CD23) (FCER2))

    别名

    FCER2

    背景

    Synonyms: Low affinity immunoglobulin epsilon Fc receptor,Fc-epsilon-RII,Lymphocyte IgE receptor,CD23,Fcer2,Fcer2a,

    Tissue Specificity: Expressed on B-cells.

    Background: CD23, also known as Fc epsilon RII, or FcεRII, is the "low-affinity" receptor for IgE, an antibody isotype involved in allergy and resistance to parasites, and is important in regulation of IgE levels. There are two forms of CD23: CD23a and CD23b. CD23a is present on follicular B cells, whereas CD23b requires IL-4 to be expressed on T-cells, monocytes, Langerhans cells, eosinophils, and macrophages. As part of a mapping of multiple probes to specific bands on chromosome 19 by fluorescence in situ hybridization, the FCE2 gene was assigned to 19p13.3. CD23 (FCE2) is a key molecule for B-cell activation and growth. It is the low-affinity receptor for IgE. The truncated molecule can be secreted, then functioning as a potent mitogenic growth factor.

    Sequence Similarities: Contains 1 C-type lectin domain.

    分子量

    49 kDa

    基因ID

    14128

    UniProt

    P20693

    途径

    Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process
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