Dystrophin 抗体 (AA 114-263)
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- 抗原 See all Dystrophin (DMD) 抗体
- Dystrophin (DMD)
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抗原表位
- AA 114-263
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This Dystrophin antibody is un-conjugated
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应用范围
- Immunohistochemistry (IHC), ELISA, Coating (Coat), Immunohistochemistry (Formalin-fixed Sections) (IHC (f))
- 特异性
- Dystrophin-glycoprotein complex (DGC) connects the F-Actin cytoskeleton on the inner surface of muscle fibers to the surrounding extracellular matrix, through the cell membrane interface. A deficiency in this protein contributes to Duchenne (DMD) and Becker (BMD) muscular dystrophies. The human dystrophin gene measures 2.4 megabases, has more than 80 exons, produces a 14 kb mRNA and contains at least 8 independent tissue-specific promoters and 2 poly A sites. The dystrophin mRNA can undergo differential splicing and produce a range of transcripts that encode a large set of proteins. Dystrophin represents approximately 0.002 % of total striated muscle protein and localizes to triadic junctions in skeletal muscle, where it is thought to influence calcium ion homeostasis and force transmission.
- 交叉反应 （详细）
- Human.
- 纯化方法
- 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
- 免疫原
- A recombinant fragment (around aa 114-263) of human DMD protein (exact sequence is proprietary)
- 克隆位点
- DMD-3243
- 亚型
- IgG1 kappa
- Top Product
- Discover our top product DMD Primary Antibody
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anti-Dystrophin (DMD) (AA 346-635) antibody
DMD 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Dystrophin (DMD) antibodyDMD 适用: 人, 小鼠, 大鼠 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Dystrophin (DMD) (AA 114-263) antibodyDMD 适用: 人 IHC, ELISA, Coat, StM 宿主: 小鼠 Monoclonal DMD-3242 unconjugated
anti-Dystrophin (DMD) (AA 1-635) antibodyDMD 适用: 人 WB, IP, ELISA 宿主: 小鼠 Monoclonal 3A11 unconjugated
anti-Dystrophin (DMD) antibodyDMD 适用: 人 IHC, IF 宿主: 兔 Monoclonal unconjugated
anti-Dystrophin (DMD) (AA 3076-3404) antibodyDMD 适用: 人, 小鼠, 大鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Dystrophin (DMD) (AA 3048-3328) antibodyDMD 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Dystrophin (DMD) (AA 114-263) antibodyDMD 适用: 人 IHC, ELISA, Coat, StM 宿主: 小鼠 Monoclonal DMD-3241 unconjugated
anti-Dystrophin (DMD) (AA 114-263) antibodyDMD 适用: 人 IHC, ELISA, Coat, StM 宿主: 小鼠 Monoclonal DMD-3245 unconjugated
anti-Dystrophin (DMD) (AA 253-597) antibodyDMD 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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Known_Application: ELISA (For coating, order Ab without BSA),Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT),(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes), Optimal dilution for a specific application should be determined.
Positive_Control: Human skeletal muscle and heart muscle tissues (IHC).
- 限制
- 仅限研究用
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- 浓度
- 1.0 mg/mL
- 缓冲液
- Prepared in 10 mM PBS, WITHOUT BSA and Azide.
- 储存液
- Azide free
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
- 有效期
- 24 months
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- 抗原
- Dystrophin (DMD)
- 别名
- DMD (DMD 产品)
- 别名
- DMD antibody, Dmd antibody, MGC83347 antibody, DKFZp459C1629 antibody, dmd antibody, MGC79631 antibody, DKFZp468A1620 antibody, Dp71 antibody, cb664 antibody, zfDYS antibody, im:6911785 antibody, zgc:110165 antibody, BMD antibody, CMD3B antibody, DXS142 antibody, DXS164 antibody, DXS206 antibody, DXS230 antibody, DXS239 antibody, DXS268 antibody, DXS269 antibody, DXS270 antibody, DXS272 antibody, DXSmh7 antibody, DXSmh9 antibody, Dp427 antibody, dys antibody, mdx antibody, pke antibody, DNADMD1 antibody, RATDMD antibody, CG17750 antibody, CG31175 antibody, CG34157 antibody, CG7240 antibody, CG7243 antibody, CG7344 antibody, DLP antibody, DLP1 antibody, DLP186 antibody, DLP2 antibody, DLP3 antibody, DmDLP antibody, DmDYS antibody, Dmel\\CG34157 antibody, Dp117 antibody, Dp186 antibody, Dp205 antibody, GI3046716 antibody, IDLP antibody, det antibody, dmDLP antibody, dmDp186 antibody, dmDys antibody, dystrophin antibody, dystrophin, gene 1 L homeolog antibody, dystrophin, gene 1 antibody, dystrophin, muscular dystrophy antibody, Dystrophin antibody, DMD antibody, LOC708073 antibody, dmd.1.L antibody, LOC465557 antibody, dmd.1 antibody, dmd antibody, Dmd antibody, Dys antibody
- 背景
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BMD, CMD3B, Duchenne muscular dystrophy (DMD), Dystrophin, Muscular dystrophy Duchenne and Becker types,Dystrophin (DMD) (Marker of Duchenne and Becker Muscular Dystrophy)
Cellular localisation: Cell Surface and Cytoplasmic - 分子量
- 427kDa
- 基因ID
- 1756, 495912
- UniProt
- P11532
- 途径
- Skeletal Muscle Fiber Development
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