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BCMA 抗体 (AA 78-184)

TNFRSF17 适用: 人 ELISA, IHC, Coat, IHC (f) 宿主: 小鼠 Monoclonal BCMA-2366 unconjugated
产品编号 ABIN6936646
发货至: 中国
  • 抗原 See all BCMA (TNFRSF17) 抗体
    BCMA (TNFRSF17) (Tumor Necrosis Factor Receptor Superfamily, Member 17 (TNFRSF17))
    抗原表位
    • 7
    • 7
    • 7
    • 6
    • 6
    • 5
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 78-184
    适用
    • 52
    • 21
    • 5
    • 1
    • 1
    • 1
    • 1
    • 1
    宿主
    • 43
    • 11
    • 9
    小鼠
    克隆类型
    • 42
    • 21
    单克隆
    标记
    • 37
    • 9
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This BCMA antibody is un-conjugated
    应用范围
    • 47
    • 37
    • 14
    • 11
    • 7
    • 6
    • 5
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    ELISA, Immunohistochemistry (IHC), Coating (Coat), Immunohistochemistry (Formalin-fixed Sections) (IHC (f))
    特异性
    The B cell maturation protein (BCMA) is a type I integral membrane protein that belongs to the tumor necrosis factor receptor (TNF-R) superfamily. It is expressed as a 184 amino acid peptide that is expressed only in mature B-lymphocytes and is located on the cis part of the Golgi apparatus. BCMA shares significant homology with TACI (transmembrane activator) within the cysteine-rich domain. TACI has been shown to bind CAML, which induces activation of NFAT (nuclear factor of activated T cells). Both BCMA and TACI have been shown to bind APRIL and TALL-1, which stimulate B cell proliferation in conjunction with other B-cell activators. When overexpressed, TALL-1 stimulates the development of systemic lupus erythaematosus (SLE).
    交叉反应 (详细)
    Human.
    纯化方法
    1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
    免疫原
    Recombinant human CD269 protein fragment (around aa 78-184) (exact sequence is proprietary)
    克隆位点
    BCMA-2366
    亚型
    IgG2c kappa
    Top Product
    Discover our top product TNFRSF17 Primary Antibody
  • 应用备注

    Known_Application: ELISA (For coating, order antibody without BSA),Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT),(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes), Optimal dilution for a specific application should be determined.

    Positive_Control: NAMALWA cells. Tonsil or gastric carcinoma (IHC).

    限制
    仅限研究用
  • 浓度
    1.0 mg/mL
    缓冲液
    Prepared in 10 mM PBS, WITHOUT BSA and Azide.
    储存液
    Azide free
    储存条件
    -20 °C,-80 °C
    储存方法
    Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
    有效期
    24 months
  • 抗原
    BCMA (TNFRSF17) (Tumor Necrosis Factor Receptor Superfamily, Member 17 (TNFRSF17))
    别名
    CD269 (TNFRSF17 产品)
    别名
    TNFRSF17 antibody, BCM antibody, BCMA antibody, CD269 antibody, TNFRSF13A antibody, Tnfrsf13 antibody, Tnfrsf13a antibody, TNF receptor superfamily member 17 antibody, tumor necrosis factor receptor superfamily, member 17 antibody, Tnfrsf17 antibody, TNFRSF17 antibody
    背景
    B-cell maturation protein, BCMA, CD269, TNR17, Tumor necrosis factor receptor superfamily member 17 (TNFRSF17),CD269 / TNFRSF17 / BCMA (B-Cell Maturation Protein)
    Cellular localisation: Cell Surface
    分子量
    20kDa
    基因ID
    608, 2556
    UniProt
    Q02223
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