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ATG5 抗体 (AA 1-119)

ATG5 适用: 人 WB, ELISA, Coat, IHC (f) 宿主: 小鼠 Monoclonal ATG5-2553 unconjugated
产品编号 ABIN6936433
发货至: 中国
  • 抗原 See all ATG5 抗体
    ATG5 (ATG5 Autophagy Related 5 (ATG5))
    抗原表位
    • 16
    • 13
    • 7
    • 6
    • 6
    • 5
    • 4
    • 4
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1-119
    适用
    • 99
    • 43
    • 35
    • 6
    • 6
    • 5
    • 5
    • 4
    • 4
    • 4
    • 4
    • 3
    • 3
    • 2
    宿主
    • 75
    • 21
    • 4
    • 1
    小鼠
    克隆类型
    • 76
    • 25
    单克隆
    标记
    • 54
    • 8
    • 7
    • 6
    • 6
    • 6
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This ATG5 antibody is un-conjugated
    应用范围
    • 76
    • 53
    • 35
    • 17
    • 16
    • 16
    • 14
    • 13
    • 10
    • 8
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Coating (Coat), Immunohistochemistry (Formalin-fixed Sections) (IHC (f))
    特异性
    The protein encoded by this gene, in combination with autophagy protein 12, functions as an E1-like activating enzyme in a ubiquitin-like conjugating system. The encoded protein is involved in several cellular processes, including autophagic vesicle formation, mitochondrial quality control after oxidative damage, negative regulation of the innate antiviral immune response, lymphocyte development and proliferation, MHC II antigen presentation, adipocyte differentiation, and apoptosis. The ATG5 protein is essential for autophagy, a process that is usually beneficial for cells to self-degrade their own components when they are no longer useful.
    交叉反应 (详细)
    Human.
    纯化方法
    1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
    免疫原
    Recombinant fragment of human ATG5 protein (around aa 1-119) (exact sequence is proprietary)
    克隆位点
    ATG5-2553
    亚型
    IgG1 kappa
    Top Product
    Discover our top product ATG5 Primary Antibody
  • 应用备注

    Known_Application: ELISA (For coating use Ab at 1-5 μg/mL, order Ab without BSA), Western Blot (1-2 μg/mL),Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 min at RT),(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes), Optimal dilution for a specific application should be determined.

    Positive_Control: K562, U-87, A431, THP-1, PANC-1, Raji or HeLa cells. Ovary, Endometrium, Colon or Duodenum.

    限制
    仅限研究用
  • 浓度
    1.0 mg/mL
    缓冲液
    Prepared in 10 mM PBS, WITHOUT BSA and Azide.
    储存液
    Azide free
    储存条件
    -20 °C,-80 °C
    储存方法
    Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
    有效期
    24 months
  • 抗原
    ATG5 (ATG5 Autophagy Related 5 (ATG5))
    别名
    ATG5 (ATG5 产品)
    别名
    APG5 antibody, APG5-LIKE antibody, APG5L antibody, ASP antibody, hAPG5 antibody, ATG5 antibody, CG1643 antibody, DmAtg5 antibody, Dmel\\CG1643 antibody, atg5 antibody, 2010107M05Rik antibody, 3110067M24Rik antibody, AW319544 antibody, Apg5l antibody, Atg5l antibody, C88337 antibody, Paddy antibody, apg5l antibody, zgc:100934 antibody, ATATG5 antibody, AUTOPHAGY 5 antibody, MKP11.20 antibody, MKP11_20 antibody, autophagy related 5 antibody, Autophagy-related 5 antibody, ATG5 autophagy related 5 homolog (S. cerevisiae) antibody, autophagy related 5 L homeolog antibody, similar to S. cerevisiae ATG5 (YPL149W) which nucleates preautophagosome formation as a conjugate with Atg12 antibody, autophagy protein Apg5 family antibody, ATG5 antibody, Atg5 antibody, atg5 antibody, atg5.L antibody, APG5 antibody
    背景
    APG5 autophagy 5 like (APG5L), Apoptosis-specific protein (ASP), ATG5, Autophagy related 5, hAPG5,ATG5 (Autophagy Marker)
    Cellular localisation: Cytoplasmic
    分子量
    32kDa
    基因ID
    9474, 486063
    UniProt
    Q9H1Y0
    途径
    Activation of Innate immune Response, Production of Molecular Mediator of Immune Response, Autophagy
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