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Caspase 3 抗体

CASP3 适用: 人, 小鼠, 大鼠 WB 宿主: 小鼠 Monoclonal CAS3836 unconjugated
产品编号 ABIN2738761
发货至: 中国
  • 抗原 See all Caspase 3 (CASP3) 抗体
    Caspase 3 (CASP3)
    适用
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    人, 小鼠, 大鼠
    宿主
    • 260
    • 39
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    小鼠
    克隆类型
    • 258
    • 48
    单克隆
    标记
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    This Caspase 3 antibody is un-conjugated
    应用范围
    • 232
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    Western Blotting (WB)
    特异性
    Human CASP3 / Caspase 3
    纯化方法
    Protein G purified
    免疫原
    The large subunit domain of human Caspase-3.
    克隆位点
    CAS3836
    亚型
    IgG1 kappa
    Top Product
    Discover our top product CASP3 Primary Antibody
  • 应用备注
    Approved: WB (2 - 4 μg/mL)

    Usage: Caspases, or cysteine-aspartic proteases, are a family of cysteine proteases that play essential roles in inflammation, apoptosis and necrosis. They are often referred to as the 'executioners of apoptosis.' Caspases are synthesized as inactive proenzymes comprising an N-terminal peptide (prodomain) together with one large and one small subunit. Active caspase-1 and -3 are heterodimers, containing two small and two large subunits. Active Caspase-3 subunits are 17kD (p17) and 12kD (p12). Pro Caspase-3 is inactive and has virtually no activity until it is cleaved by an initiator caspase. It is activated by Caspases -8, -9 and -10 ('initiator caspases') and then effects apoptosis by cleaving targeted cellular proteins. This antibody will detect the pro form and p17 and p12 active forms of Caspase-3.
    说明

    Target Species of Antibody: Human

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    Lot specific
    缓冲液
    PBS,  pH 7.4, 0.1 mg/mL BSA, 0.05 % sodium azide
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    avoid freeze thaw cycles
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Avoid freeze-thaw cycles.
  • 抗原
    Caspase 3 (CASP3)
    别名
    CASP3 / Caspase 3 (CASP3 产品)
    别名
    CPP32 antibody, CPP32B antibody, SCA-1 antibody, A830040C14Rik antibody, AC-3 antibody, Apopain antibody, CC3 antibody, Caspase-3 antibody, Lice antibody, Yama antibody, mldy antibody, xcpp32 antibody, casp3 antibody, zgc:100890 antibody, CASP-3 antibody, caspase-3 antibody, caspase 3 antibody, caspase 3 S homeolog antibody, caspase 3, apoptosis-related cysteine peptidase a antibody, caspase 3, apoptosis-related cysteine peptidase antibody, CASP3 antibody, Casp3 antibody, casp3.S antibody, casp3a antibody
    背景
    Name/Gene ID: CASP3
    Subfamily: Cysteine C14
    Family: Protease

    Synonyms: CASP3, Apopain, CASP-3, Caspase-3, CPP32B, CPP32, Cysteine protease CPP32, SCA-1, SREBP cleavage activity 1, Yama, Procaspase3, Caspase 3, CPP-32, PARP cleavage protease, Protein Yama
    基因ID
    836
    途径
    Apoptosis, Caspase Cascade in Apoptosis, Sensory Perception of Sound, ER-Nucleus Signaling, Positive Regulation of Endopeptidase Activity, Activated T Cell Proliferation
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