电话:
400-7060-959
传真:
+86 10 56315212-8813
电子邮件:
orders@antibodies-online.cn

CYP11A1 抗体 (AA 288-337)

CYP11A1 适用: 人 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN6744438
发货至: 中国
  • 抗原 See all CYP11A1 抗体
    CYP11A1 (Cytochrome P450, Family 11, Subfamily A, Polypeptide 1 (CYP11A1))
    抗原表位
    • 16
    • 6
    • 5
    • 4
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 288-337
    适用
    • 47
    • 25
    • 24
    • 17
    • 2
    • 2
    • 1
    宿主
    • 49
    • 3
    克隆类型
    • 51
    • 1
    多克隆
    标记
    • 33
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This CYP11A1 antibody is un-conjugated
    应用范围
    • 49
    • 15
    • 14
    • 13
    • 13
    • 9
    • 8
    • 7
    • 6
    • 5
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    品牌
    IHC-plus™
    特异性
    Human CYP11A1
    预测反应
    Percent identity by BLAST analysis: Human (100%).
    纯化方法
    Immunoaffinity purified
    免疫原
    Synthetic peptide located between aa288-337 of human CYP11A1 (P05108, NP_000772). Percent identity by BLAST analysis: Human, Chimpanzee, Gorilla (100%), Monkey (92%).

    Type of Immunogen: Synthetic peptide
    亚型
    IgG
    Top Product
    Discover our top product CYP11A1 Primary Antibody
  • 应用备注
    Approved: IHC, IHC-P (5 μg/mL), WB (1 μg/mL)

    Usage: Immunohistochemistry: This antibody was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in  pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen. The stained slides were evaluated by a pathologist to confirm staining specificity. The optimal working concentration for this antibody was determined to be 5 μg/mL. ELISA titer using peptide based assay: 1:1562500. Western Blot: Suggested dilution at 1 μg/mL in 5 % skim milk / PBS buffer, and HRP conjugated anti-Rabbit IgG should be diluted in 1:50000 - 100000 as second antibody.
    说明

    Target Species of Antibody: Human

    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Distilled Water.
    浓度
    Lot specific
    缓冲液
    Lyophilized from PBS with 2 % sucrose
    注意事项
    Avoid repeat freeze-thaw cycles.
    储存条件
    4 °C,-20 °C
    储存方法
    Long term: -20°C, the use of 50% glycerol is recommended if storing aliquots in -20°C for long term use (up to 1 year)
    Short term (less than 1 week): 4°C. Avoid freeze-thaw cycles.
  • Jia, Domenico, Takeda, Han, Wang, Armstrong, Reisdorph, OConnor, Lucas, Gelfand: "Steroidogenic enzyme Cyp11a1 regulates Type 2 CD8+ T cell skewing in allergic lung disease." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 110, Issue 20, pp. 8152-7, (2013) (PubMed).

  • 抗原
    CYP11A1 (Cytochrome P450, Family 11, Subfamily A, Polypeptide 1 (CYP11A1))
    别名
    P450SCC / CYP11A1 (CYP11A1 产品)
    别名
    CYP11A antibody, CYP11A1 antibody, CYPXIA1 antibody, P450SCC antibody, Cyp11a antibody, Cypxia1 antibody, D9Ertd411e antibody, P450scc antibody, Scc antibody, cscc antibody, P450(scc) antibody, SSC antibody, cytochrome P450 family 11 subfamily A member 1 antibody, cholesterol side-chain cleavage enzyme, mitochondrial-like antibody, cytochrome P450 cholesterol side-chain cleavage antibody, cytochrome P450, family 11, subfamily a, polypeptide 1 antibody, cytochrome P450, family 11, subfamily A, polypeptide 1 antibody, CYP11A1 antibody, LOC101827747 antibody, Cyp11a1 antibody
    背景
    Name/Gene ID: CYP11A1
    Family: Cytochrome P450

    Synonyms: CYP11A1, Cholesterol 20-22 desmolase, Cholesterol desmolase, Cytochrome P450 11A1, Cytochrome P450C11A1, CYP11A, Cytochrome P450(scc), p450SCC, Steroid 20-22-lyase, CYPXIA1
    基因ID
    1583
    NCBI登录号
    NP_000772
    UniProt
    P05108
    途径
    Metabolism of Steroid Hormones and Vitamin D, Steroid Hormone Biosynthesis, C21-Steroid Hormone Metabolic Process, Cellular Response to Molecule of Bacterial Origin
You are here:
客服