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CYP11A1 产品

(Cytochrome P450, Family 11, Subfamily A, Polypeptide 1 (CYP11A1))

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This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the mitochondrial inner membrane and catalyzes the conversion of cholesterol to pregnenolone, the first and rate-limiting step in the synthesis of the steroid hormones. Two transcript variants encoding different isoforms have been found for this gene. The cellular location of the smaller isoform is unclear since it lacks the mitochondrial-targeting transit peptide. [provided by RefSeq, Jul 2008].

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Featured CYP11A1 Categories

CYP11A1 抗体

High quality antibodies with extensive validation data.

CYP11A1 ELISA试剂盒

Reliable ELISA kits for a wide range of species.

CYP11A1 蛋白

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended CYP11A1 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Cow, Human, Mouse, Rat
Application WB, IF (p), IHC (p), FACS, IF (cc), IHC (fro)
Validations
  • (5)
  • (5)
Cat. No. ABIN701530
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IHC, IF
Validations
  • (9)
Cat. No. ABIN1512804
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, IHC, IHC (p)
Validations
  • (1)
  • (4)
Cat. No. ABIN6744438
Quantity 100 μL
Datasheet Datasheet

Recommended CYP11A1 ELISA试剂盒

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6966228
Quantity 96 tests
Datasheet Datasheet
Reactivity Rat
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6966229
Quantity 96 tests
Datasheet Datasheet
Reactivity Rat
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6955234
Quantity 96 tests
Datasheet Datasheet

Recommended CYP11A1 蛋白

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1350923
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1350925
Quantity 10 μg
Datasheet Datasheet
Reactivity Rat
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7407913
Quantity 100 μg
Datasheet Datasheet

Latest Publications for our CYP11A1 Products

Sagaradze, Basalova, Kirpatovsky, Ohobotov, Grigorieva, Balabanyan, Kamalov, Efimenko: "Application of rat cryptorchidism model for the evaluation of mesenchymal stromal cell secretome regenerative potential." in: Biomedicine & pharmacotherapy, Vol. 109, pp. 1428-1436, (2019) (PubMed).

Ommati, Heidari, Jamshidzadeh, Zamiri, Sun, Sabouri, Wang, Ahmadi, Javanmard, Seifi, Mousapour, Yeganeh: "Dual effects of sulfasalazine on rat sperm characteristics, spermatogenesis, and steroidogenesis in two experimental models." in: Toxicology letters, Vol. 284, pp. 46-55, (2018) (PubMed).

Lin, Liu, Guo, Liu, Mi, Zhang: "Promotion of the prehierarchical follicle growth by postovulatory follicles involving PGE2 -EP2 signaling in chickens." in: Journal of cellular physiology, Vol. 233, Issue 11, pp. 8984-8995, (2018) (PubMed).

Medwid, Guan, Yang: "Prenatal exposure to bisphenol A disrupts adrenal steroidogenesis in adult mouse offspring." in: Environmental toxicology and pharmacology, Vol. 43, pp. 203-8, (2016) (PubMed).

Mahata, Zhang, Kolodziejczyk, Proserpio, Haim-Vilmovsky, Taylor, Hebenstreit, Dingler, Moignard, Göttgens, Arlt, McKenzie, Teichmann: "Single-cell RNA sequencing reveals T helper cells synthesizing steroids de novo to contribute to immune homeostasis." in: Cell reports, Vol. 7, Issue 4, pp. 1130-42, (2014) (PubMed).

LaVoie, Whitfield, Shi, King, Bose, Hui: "STARD6 is expressed in steroidogenic cells of the ovary and can enhance de novo steroidogenesis." in: Experimental biology and medicine (Maywood, N.J.), Vol. 239, Issue 4, pp. 430-5, (2014) (PubMed).

Jia, Domenico, Takeda, Han, Wang, Armstrong, Reisdorph, OConnor, Lucas, Gelfand: "Steroidogenic enzyme Cyp11a1 regulates Type 2 CD8+ T cell skewing in allergic lung disease." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 110, Issue 20, pp. 8152-7, (2013) (PubMed).

Hu, Dong, Chen, Lu, Han, Qiu, Chen, Qin, Li, Gu, Xia, Sun, Li, Wang: "Low-dose monobutyl phthalate stimulates steroidogenesis through steroidogenic acute regulatory protein regulated by SF-1, GATA-4 and C/EBP-beta in mouse Leydig tumor cells." in: Reproductive biology and endocrinology : RB&E, Vol. 11, pp. 72, (2013) (PubMed).

He, Xu, Chen, Liu, Xi: "Abnormal apoptosis of trophoblastic cells is related to the up-regulation of CYP11A gene in placenta of preeclampsia patients." in: PLoS ONE, Vol. 8, Issue 3, pp. e59609, (2013) (PubMed).

Arboleda, Lee, Parnaik, Fleming, Banerjee, Ferraz-de-Souza, Délot, Rodriguez-Fernandez, Braslavsky, Bergadá, DellAngelica, Nelson, Martinez-Agosto, Achermann, Vilain: "Mutations in the PCNA-binding domain of CDKN1C cause IMAGe syndrome." in: Nature genetics, Vol. 44, Issue 7, pp. 788-92, (2012) (PubMed).

Synonyms and alternative names related to CYP11A1

cytochrome P450 family 11 subfamily A member 1 (CYP11A1), cholesterol side-chain cleavage enzyme, mitochondrial-like (LOC101827747), cytochrome P450 cholesterol side-chain cleavage (CYP11A1), cytochrome P450, family 11, subfamily a, polypeptide 1 (Cyp11a1), cytochrome P450, family 11, subfamily A, polypeptide 1 (CYP11A1), cscc, CYP11A, Cyp11a, CYP11A1, CYPXIA1, Cypxia1, D9Ertd411e, P450(scc), P450SCC, P450scc, Scc, SSC

Protein level used designations for CYP11A1

  • cholesterol side-chain cleavage enzyme, mitochondrial
  • cytochrome P450 11A1
  • cytochrome P-450 cholesterol side-chain cleavage enzyme
  • Cholesterol desmolase
  • Cytochrome P450 11A1
  • Cytochrome P450(scc)
  • cholesterol desmolase
  • cytochrome P450(scc)
  • cholesterol 20-22 desmolase
  • cholesterol monooxygenase (side-chain cleaving)
  • cytochrome P450, subfamily XIA (cholesterol side chain cleavage)
  • cytochrome P450C11A1
  • steroid 20-22-lyase
  • cholesterol side chain cleavage
  • cytochrome P450 side-chain cleavage enzyme
  • cytochrome P450, 11a, cholesterol side-chain cleavage
  • P450(scc)
  • cholesterol side-chain cleavage cytochrome P450
  • cytochrome P450 11a cholesterol side chain cleavage
  • cytochrome P450 subfamily 11A
  • Cholesterol side-chain cleavage enzyme, mitochondrial
  • CYPXIA1
  • cytochrome P450scc
  • cytochrome P450 family 11 subfamily A polypeptide 1
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