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CYP17A1 产品

(Cytochrome P450, Family 17, Subfamily A, Polypeptide 1 (CYP17A1))
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum. It has both 17alpha-hydroxylase and 17,20-lyase activities and is a key enzyme in the steroidogenic pathway that produces progestins, mineralocorticoids, glucocorticoids, androgens, and estrogens. Mutations in this gene are associated with isolated steroid-17 alpha-hydroxylase deficiency, 17-alpha-hydroxylase/17,20-lyase deficiency, pseudohermaphroditism, and adrenal hyperplasia. [provided by RefSeq, Jul 2008].

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Featured CYP17A1 Categories

CYP17A1 抗体

High quality antibodies with extensive validation data.

CYP17A1 ELISA试剂盒

Reliable ELISA kits for a wide range of species.

CYP17A1 蛋白

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended CYP17A1 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Mouse, Rat
Application WB, ELISA, IHC (p)
Validations
  • (3)
  • (5)
Cat. No. ABIN720071
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IHC, IF
Validations
  • (4)
Cat. No. ABIN7170749
Quantity 100 μg
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, ELISA, IHC, IF, ICC
Validations
  • (4)
Cat. No. ABIN6258050
Quantity 100 μL
Datasheet Datasheet

Recommended CYP17A1 ELISA试剂盒

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Rat
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6966231
Quantity 96 tests
Datasheet Datasheet
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6955239
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Competition ELISA
Validations
Cat. No. ABIN511584
Quantity 96 tests
Datasheet Datasheet

Recommended CYP17A1 蛋白

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1350928
Quantity 25 μg
Datasheet Datasheet
Reactivity Mouse
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7419073
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7418737
Quantity 100 μg
Datasheet Datasheet

Latest Publications for our CYP17A1 Products

Han, Xie, Zhang, Zhang, Zhang, Han, Yuan, Weng: "Seasonal expression of P450c17 and 5α-reductase-2 in the scented gland of male muskrats (Ondatra zibethicus)." in: General and comparative endocrinology, Vol. 254, pp. 60-67, (2018) (PubMed).

Zhang, Zhao, Zhang, Hao, Yu, Min, Li, Ma, Chen, Yi, Tang, Meng, Liu, Wang, Shen, Zhang: "Decrease in male mouse fertility by hydrogen sulfide and/or ammonia can Be inheritable." in: Chemosphere, Vol. 194, pp. 147-157, (2018) (PubMed).

Ghazi, Hosseinpanah, Abdi, Hedayati, Hasheminia, Ghazi, Azizi: "Effect of Different Doses of Oral Cholecalciferol on Serum 1,25(OH)2D in Vitamin D Deficient Schoolchildren." in: Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et métabolisme, Vol. 48, Issue 6, pp. 394-8, (2017) (PubMed).

Babischkin, Aberdeen, Pepe, Albrecht: "Estrogen Suppresses Interaction of Melanocortin 2 Receptor and Its Accessory Protein in the Primate Fetal Adrenal Cortex." in: Endocrinology, Vol. 157, Issue 12, pp. 4588-4601, (2017) (PubMed).

Spade, Hall, Saffarini, Huse, McDonnell, Boekelheide: "Differential response to abiraterone acetate and di-n-butyl phthalate in an androgen-sensitive human fetal testis xenograft bioassay." in: Toxicological sciences : an official journal of the Society of Toxicology, Vol. 138, Issue 1, pp. 148-60, (2014) (PubMed).

Efstathiou, Titus, Wen, Hoang, Karlou, Ashe, Tu, Aparicio, Troncoso, Mohler, Logothetis: "Molecular characterization of enzalutamide-treated bone metastatic castration-resistant prostate cancer." in: European urology, Vol. 67, Issue 1, pp. 53-60, (2014) (PubMed).

Wilsher, Stansfield, Greenwood, Trethowan, Anderson, Wooding, Allen: "Ovarian and placental morphology and endocrine functions in the pregnant giraffe (Giraffa camelopardalis)." in: Reproduction (Cambridge, England), Vol. 145, Issue 6, pp. 541-54, (2013) (PubMed).

Efstathiou, Titus, Tsavachidou, Tzelepi, Wen, Hoang, Molina, Chieffo, Smith, Karlou, Troncoso, Logothetis: "Effects of abiraterone acetate on androgen signaling in castrate-resistant prostate cancer in bone." in: Journal of clinical oncology : official journal of the American Society of Clinical Oncology, Vol. 30, Issue 6, pp. 637-43, (2012) (PubMed).

Ohnishi, Ogawa, Saibara, Nishioka, Kariya, Fukumoto, Onishi, Yoshida: "CYP17 polymorphism as a risk factor of tamoxifen-induced hepatic steatosis in breast cancer patients." in: Oncology reports, Vol. 13, Issue 3, pp. 485-9, (2005) (PubMed).

Synonyms and alternative names related to CYP17A1

cytochrome P450 17A1 (CpipJ_CPIJ010537), cytochrome P450 17A1 (CpipJ_CPIJ010543), cytochrome P450 17A1 (PTRG_02047), cytochrome P450, family 17, subfamily A, polypeptide 1 (cyp17a1), steroidogenic cytochrome P450 17-hydroxylase/lyase (cyp17), cytochrome P450 family 17 subfamily A member 1 L homeolog (cyp17a1.L), cytochrome P450 family 17 subfamily A member 1 (cyp17a1), cytochrome P-450 17 alpha-hydroxylase/C17,20-lyase (CYP17A1), cytochrome P450 17A1 (CYP17A1), cytochrome P450 family 17 subfamily A member 1 (CYP17A1), cytochrome P450, family 17, subfamily A, polypeptide 1 (CYP17A1), cytochrome P450, family 17, subfamily a, polypeptide 1 (Cyp17a1), cytochrome P450c17 (CYP17A1), CPT7, cyp17, CYP17, Cyp17, cyp17a1, CYPXVII, P450-C17, P450c17, P450C17, p450c17, P45017A1, S17AH, wu:fi13g04, wu:fi17b11, wu:fi31c08, zgc:66494, zgc:136516

Protein level used designations for CYP17A1

  • cytochrome P450 17A1
  • steroid 17-alpha-hydroxylase/17,20 lyase
  • CYPXVII
  • cytochrome P450c17
  • cytochrome P450-C17
  • cytochrome P450 XVIIA1
  • steroid 17-alpha-monooxygenase
  • steroidogenic cytochrome P450 17-hydroxylase/lyase
  • Cytochrome P450 17A1
  • Steroid 17-alpha-hydroxylase/17,20 lyase
  • cytochrome P450 steroid 17-alpha-hydroxylase/17,20 lyase
  • cytochrome P450, family 17, subfamily A, polypeptide 1
  • 17-alpha-hydroxyprogesterone aldolase
  • 17-alpha-hydroxylase cytochrome P450
  • cytochrome P450, subfamily XVII (steroid 17-alpha-hydroxylase), adrenal hyperplasia
  • cytochrome p450 XVIIA1
  • cytochrome P450 steroid 17alpha-hydroxylase/17,20 lyase
  • cytochrome P450, subfamily XVII
  • steroid 17-alpha-hydroxylase
  • cytochrome P450, 17
  • cytochrome P450, 17a1
  • steroid 17-alpha hydroxylase
  • Cytochrome P450, subfamily XVII
  • P450-C17
  • P45017alpha
  • P450c17
  • cytochrome P450, subfamily 17
  • cytochrome P450 17 alpha-hydroxylase
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