AP2A2 抗体 (AA 21-150) (Cy3)
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- 抗原 See all AP2A2 抗体
- AP2A2 (Adaptor-Related Protein Complex 2, alpha 2 Subunit (AP2A2))
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抗原表位
- AA 21-150
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适用
- 人, 小鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This AP2A2 antibody is conjugated to Cy3
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应用范围
- Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
- 特异性
- Based on the similarity among the Alpha2-Adaptin proteins, this antibody will bind both AP2A1 and AP2A2.
- 交叉反应
- 人, 小鼠
- 预测反应
- Rat,Cow,Horse,Rabbit
- 纯化方法
- Purified by Protein A.
- 免疫原
- KLH conjugated synthetic peptide derived from human AP2A2
- 亚型
- IgG
- Top Product
- Discover our top product AP2A2 Primary Antibody
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- 应用备注
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- 有效期
- 12 months
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- 抗原
- AP2A2 (Adaptor-Related Protein Complex 2, alpha 2 Subunit (AP2A2))
- 别名
- alpha2 Adaptin (AP2A2 产品)
- 别名
- MGC99219 antibody, ADTAB antibody, CLAPA2 antibody, HIP-9 antibody, HIP9 antibody, HYPJ antibody, 2410074K14Rik antibody, AF006990 antibody, AW146353 antibody, Adtab antibody, C78001 antibody, L25 antibody, adaptor related protein complex 2 alpha 2 subunit antibody, adaptor related protein complex 2 alpha 2 subunit L homeolog antibody, adaptor-related protein complex 2, alpha 2 subunit antibody, AP2A2 antibody, ap2a2.L antibody, Ap2a2 antibody
- 背景
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Synonyms: AP-2 complex subunit alpha-2, 100 kDa coated vesicle protein C, Adaptor protein complex AP-2 subunit alpha-2, Adaptor-related protein complex 2 subunit alpha-2, Alpha-adaptin C, Alpha2-adaptin, Clathrin assembly protein complex 2 alpha-C large chain, Huntingtin yeast partner J, Huntingtin-interacting protein 9, HIP-9, Huntingtin-interacting protein J, Plasma membrane adaptor HA2/AP2 adaptin alpha C subunit, AP2A2, ADTAB, CLAPA2, AP-2 complex subunit alpha-1, 100 kDa coated vesicle protein A, Adaptor protein complex AP-2 subunit alpha-1, Adaptor-related protein complex 2 subunit alpha-1, Alpha-adaptin A, Alpha1-adaptin, Clathrin assembly protein complex 2 alpha-A large chain, Plasma membrane adaptor HA2/AP2 adaptin alpha A subunit, AP2A1, ADTAA, CLAPA1
Background: Clathrin-mediated endocytosis is the pathway by which many receptors for nutrients and hormones are internalized to be recycled or down-regulated. During formation of clathrin coated membranes, clathrin co-assembles with heterotetrameric molecules known as assembly polypeptides (APs) or adaptors which form a layer of protein coat between the clathrin lattice and the membrane. There are two characterized adaptors AP1 and AP2. AP1 is associated with clathrin coated vesicles at the trans-Golgi network and AP2 is associated with the endocytic clathrin coated vesicles at the plasma membrane and has been shown to specifically interact with Shc and EGF receptor. AP2 is composed of four subunits, two separate 100 kDa gene products with similar domain structures (alpha and beta adaptin) and a 50 and 17 kDa subunit. There are two alpha-adaptin genes, alpha A and alpha C which have a tissue specific pattern of expression.
- 基因ID
- 161
- 途径
- EGFR Signaling Pathway, Neurotrophin Signaling Pathway, EGFR Downregulation, SARS-CoV-2 Protein Interactome
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