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ATF3 抗体 (AA 51-150)

Name: ATF3 抗体 (AA 51-150)
SKU: ABIN669561
Availability: OutOfStock

ATF3 适用: 人, 小鼠, 大鼠 WB, FACS, IHC (p), IF (p) 宿主: 兔 Polyclonal unconjugated

Lane 1: mouse lung lysate Lane 2: mouse brain lysate probed with Rabbit Anti-ATF3 Polyclonal Antibody, Unconjugated at 1:5000 for 90 min at 37˚C.

Formalin-fixed and paraffin embedded human colon cancer labeled with Anti-ATF3 Polyclonal Antibody, Unconjugated (ABIN669561) at 1:200 followed by conjugation to the secondary antibody and DAB staining

IHC

Formalin-fixed and paraffin embedded human colon carcinoma labeled with Anti-ATF3 Polyclonal Antibody, Unconjugated (ABIN669561) at 1:200 followed by conjugation to the secondary antibody and DAB staining

IHC

Formalin-fixed and paraffin-embedded rat brain labeled with Anti-ATF3 Polyclonal Antibody, Unconjugated (ABIN669561) 1:200, overnight at 4°C, The secondary antibody was Goat Anti-Rabbit IgG, Cy3 conjugated used at 1:200 dilution for 40 minutes at 37°C.

4 images

(5 references)

产品编号 ABIN669561

发货至: 中国

Datasheet as PDF

抗原 See all ATF3 抗体

ATF3 (Activating Transcription Factor 3 (ATF3))
抗原表位
15

14

10

8

7

4

1

1

1

1

1

1

1

1
AA 51-150
适用
63

26

24

4

4

3

3

2

2

2

2

1
人, 小鼠, 大鼠
宿主
56

8
兔
Compatible Secondaries
克隆类型
55

9
多克隆
标记
35

5

4

4

3

2

1

1

1

1

1

1

1

1

1

1

1
This ATF3 antibody is un-conjugated
应用范围
56

29

28

15

12

6

5

5

4

2

1

1

1

1
Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

交叉反应

人, 小鼠, 大鼠

纯化方法

Purified by Protein A.

免疫原

KLH conjugated synthetic peptide derived from human ATF3

亚型

IgG
anti-Activating Transcription Factor 3 (ATF3) (AA 1-181) antibody
ATF3 适用: 人 WB, ELISA, RNAi 宿主: 小鼠 Monoclonal 6B8 unconjugated

anti-Activating Transcription Factor 3 (ATF3) (AA 1-181) antibody
ATF3 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated

anti-Activating Transcription Factor 3 (ATF3) (AA 1-181) antibody
ATF3 适用: 人 WB, ELISA, IHC, FACS, ICC 宿主: 小鼠 Monoclonal 5A9B9 unconjugated

anti-Activating Transcription Factor 3 (ATF3) (AA 140-168) antibody
ATF3 适用: 人 WB, ELISA, FACS 宿主: 兔 Polyclonal unconjugated

anti-Activating Transcription Factor 3 (ATF3) (AA 1-181) antibody
ATF3 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated

anti-Activating Transcription Factor 3 (ATF3) (AA 113-130) antibody
ATF3 适用: 人 WB, ELISA, IHC, FM 宿主: 兔 Polyclonal unconjugated

anti-Activating Transcription Factor 3 (ATF3) (C-Term) antibody
ATF3 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, ICC, IF 宿主: 兔 Polyclonal unconjugated

anti-Activating Transcription Factor 3 (ATF3) (Middle Region) antibody
ATF3 适用: 人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 马, 兔, 斑马鱼, Saccharomyces cerevisiae WB 宿主: 兔 Polyclonal unconjugated

anti-Activating Transcription Factor 3 (ATF3) (AA 140-168), (C-Term) antibody
ATF3 适用: 人 WB, FACS 宿主: 兔 Polyclonal unconjugated

anti-Activating Transcription Factor 3 (ATF3) (C-Term) antibody
ATF3 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated

应用备注

WB 1:300-5000
FCM 1:20-100
IHC-P 1:200-400
IF(IHC-P) 1:50-200

限制

仅限研究用
状态

Liquid

浓度

1 μg/μL

缓冲液

0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

储存液

ProClin

注意事项

This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

储存条件

4 °C,-20 °C

储存方法

Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

有效期

12 months
Smith, Seto, Vivekanandan-Giri, Yuan, Playford, Manna, Hasni, Kuai, Mehta, Schwendeman, Pennathur, Kaplan et al.: "Lupus high-density lipoprotein induces proinflammatory responses in macrophages by binding lectin-like oxidised low-density lipoprotein receptor 1 and failing to promote activating transcription ..." in: Annals of the rheumatic diseases, (2016) (PubMed).

Aguirre, López-Alonso, González-López, Amado-Rodríguez, Batalla-Solís, Astudillo, Blázquez-Prieto, Fernández, Galván, dos Santos, Albaiceta: "Defective autophagy impairs ATF3 activity and worsens lung injury during endotoxemia." in: Journal of molecular medicine (Berlin, Germany), Vol. 92, Issue 6, pp. 665-76, (2014) (PubMed).

Yuan, Han, Cong, Ge, Ma, Dai, Li, Bi: "Docetaxel-loaded solid lipid nanoparticles suppress breast cancer cells growth with reduced myelosuppression toxicity." in: International journal of nanomedicine, Vol. 9, pp. 4829-46, (2014) (PubMed).

Hu, Li, Li: "MARVELD1 Inhibits Nonsense-Mediated RNA Decay by Repressing Serine Phosphorylation of UPF1." in: PLoS ONE, Vol. 8, Issue 6, pp. e68291, (2013) (PubMed).

Feng, Sun, Wu, Lu, Qu, Sun, Tian, Zhang, Li, Liu: "Upregulation of ATF-3 is correlated with prognosis and proliferation of laryngeal cancer by regulating Cyclin D1 expression." in: International journal of clinical and experimental pathology, Vol. 6, Issue 10, pp. 2064-70, (2013) (PubMed).
抗原

ATF3 (Activating Transcription Factor 3 (ATF3))

别名

ATF3 (ATF3 产品)

别名

zgc:55526 antibody, ATF3 antibody, LRG-21 antibody, LRF-1 antibody, LRFI antibody, atf-3 antibody, activating transcription factor 3 antibody, activating transcription factor 3 L homeolog antibody, atf3 antibody, ATF3 antibody, Atf3 antibody, atf3.L antibody

背景

Synonyms: Cyclic AMP-dependent transcription factor ATF-3, cAMP-dependent transcription factor ATF-3, Activating transcription factor 3, ATF3
Background: This protein binds the cAMP response element (CRE) (consensus: 5'-GTGACGT[AC][AG]-3'), a sequence present in many viral and cellular promoters. Represses transcription from promoters with ATF sites. It may repress transcription by stabilizing the binding of inhibitory cofactors at the promoter. Isoform 2 activates transcription presumably by sequestering inhibitory cofactors away from the promoters.

基因ID

467

UniProt

P18847

途径

Myometrial Relaxation and Contraction, ER-Nucleus Signaling, Unfolded Protein Response