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SCN9A 抗体 (C-Term)

SCN9A 适用: 人 IHC, WB, IP, FM 宿主: 小鼠 Monoclonal S68-6 unconjugated
产品编号 ABIN6656787
发货至: 中国
  • 抗原 See all SCN9A 抗体
    SCN9A (Sodium Channel, Voltage-Gated, Type IX, alpha Subunit (SCN9A))
    抗原表位
    • 11
    • 5
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    适用
    • 40
    • 14
    • 10
    • 1
    • 1
    • 1
    宿主
    • 25
    • 16
    • 1
    • 1
    小鼠
    克隆类型
    • 27
    • 16
    单克隆
    标记
    • 22
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This SCN9A antibody is un-conjugated
    应用范围
    • 24
    • 21
    • 14
    • 12
    • 12
    • 11
    • 10
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    Immunohistochemistry (IHC), Western Blotting (WB), Immunoprecipitation (IP), Fluorescence Microscopy (FM)
    交叉反应
    人, 小鼠, 大鼠
    纯化方法
    Anti-NAV1.7 Antibody was purified by Protein G chromatography. A BLAST analysis was used to suggest cross-reactivity with NAV1.7 from Human, Rat, and Mouse based on 100% homology with the immunizing sequence. No cross-reactivity against other Nav channels. Cross-reactivity with NAV1.7 from other sources has not been determined. Channels and Transporters research.
    免疫原

    Immunogen: Nav1.7 Antibody was produced in mice by repeated immunizations raised against a fusion protein corresponding to the cytoplasmic C-terminus region of human Nav1.7.

    Immunogen Type: Recombinant Protein

    克隆位点
    S68-6
    亚型
    IgG1
    Top Product
    Discover our top product SCN9A Primary Antibody
  • 应用备注

    Immunohistochemistry Dilution: 0.1-1.0 μg/mL

    Application Note: Anti-NAV1.7 Antibody is suitable for use in WB, IP, and IF microscopy. Expect a band approximately ~230 kDa on specific lysates. Specific conditions for reactivity should be optimized by the end user.

    Immunoprecipitation Dilution: User Optimized

    Western Blot Dilution: 1-10 μg/mL

    IF Microscopy Dilution: 1.0-10 μg/mL

    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液

    Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2

    Stabilizer: 50 % (v/v) Glycerol

    0.09 % (w/v) Sodium Azide
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    RT,4 °C,-20 °C
    储存方法
    Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.
  • 抗原
    SCN9A (Sodium Channel, Voltage-Gated, Type IX, alpha Subunit (SCN9A))
    别名
    NAV1.7 (SCN9A 产品)
    别名
    SCN9A antibody, DKFZp459G084 antibody, Nav1.7 antibody, PN1 antibody, mKIAA4197 antibody, Scn2a antibody, ETHA antibody, FEB3B antibody, GEFSP7 antibody, NE-NA antibody, NENA antibody, SFNP antibody, sodium channel, voltage-gated, type IX, alpha subunit antibody, sodium voltage-gated channel alpha subunit 9 antibody, sodium channel protein type 9 subunit alpha antibody, sodium channel, voltage-gated, type IX, alpha antibody, SCN9A antibody, LOC100016648 antibody, Scn9a antibody
    背景

    Synonyms: ETHA, hNE Na, NENA, PN1, SCN9A, voltage gated sodium channel subunit alpha Nav1.7, peripheral sodium channel 1, neuroendocrine sodium channel, Sodium channel protein type 9 subunit alpha

    Background: Nav1.7 is a voltage-gated sodium channel and plays a critical role in the generation and conduction of action potentials and is thus important for electrical signaling by most excitable cells. Therapeutically, the association of pain insensitivity with the loss of function of a certain sodium channel may have implications. Since Nav1.7 is not present in cardiac muscle or neurons in the central nervous system, blockers of Nav1.7 will not have direct action on these cells and thus can have less side effects than current pain medications. By performing more studies, there is a possibility to develop a new generation of drugs that can reduce the pain intensity in animals.

    Gene Name: Scn9a

    基因ID
    6335
    NCBI登录号
    NP_002968
    UniProt
    Q15858
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