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SCN9A 抗体 (AA 1751-1946) (APC)

SCN9A 适用: 人 IHC, WB, IF, IP, ICC, AA 宿主: 小鼠 Monoclonal N68-6 (Formerly S68-6) APC
产品编号 ABIN2483096
发货至: 中国
  • 抗原 See all SCN9A 抗体
    SCN9A (Sodium Channel, Voltage-Gated, Type IX, alpha Subunit (SCN9A))
    抗原表位
    • 11
    • 5
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1751-1946
    适用
    • 41
    • 14
    • 10
    • 1
    • 1
    • 1
    宿主
    • 25
    • 17
    • 1
    • 1
    小鼠
    克隆类型
    • 27
    • 17
    单克隆
    标记
    • 23
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This SCN9A antibody is conjugated to APC
    应用范围
    • 25
    • 22
    • 14
    • 12
    • 12
    • 12
    • 10
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Immunohistochemistry (IHC), Western Blotting (WB), Immunofluorescence (IF), Immunoprecipitation (IP), Immunocytochemistry (ICC), Antibody Array (AA)
    特异性
    Detects ~230 kDa. No cross-reactivity against other Nav channels.
    交叉反应
    Hamster, 人, 小鼠, 大鼠
    纯化方法
    Protein G Purified
    免疫原
    Fusion protein amino acids 1751-1946 (C-terminus) of human Nav1.7
    克隆位点
    N68-6 (Formerly S68-6)
    亚型
    IgG1
    Top Product
    Discover our top product SCN9A Primary Antibody
  • 应用备注
    • WB (1:1000)
    • IHC (1:1000)
    • ICC/IF (1:100)
    • optimal dilutions for assays should be determined by the user.
    说明

    1 μg/ml of ABIN2483096 was sufficient for detection of Nav1.7 in 10 μg of HEK-293 cell lysate transiently expressing Nav1.7 by colorimetric immunoblot analysis using Goat anti-mouse IgG:HRP as the secondary antibody.

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    PBS pH 7.4, 50 % glycerol, 0.09 % sodium azide, Storage buffer may change when conjugated
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C
    储存方法
    Conjugated antibodies should be stored at 4°C
  • 抗原
    SCN9A (Sodium Channel, Voltage-Gated, Type IX, alpha Subunit (SCN9A))
    别名
    Nav1.7 (SCN9A 产品)
    别名
    SCN9A antibody, DKFZp459G084 antibody, Nav1.7 antibody, PN1 antibody, mKIAA4197 antibody, Scn2a antibody, ETHA antibody, FEB3B antibody, GEFSP7 antibody, NE-NA antibody, NENA antibody, SFNP antibody, sodium channel, voltage-gated, type IX, alpha subunit antibody, sodium voltage-gated channel alpha subunit 9 antibody, sodium channel protein type 9 subunit alpha antibody, sodium channel, voltage-gated, type IX, alpha antibody, SCN9A antibody, LOC100016648 antibody, Scn9a antibody
    背景
    Nav1.7 is a voltage-gated sodium channel and plays a critical role in the generation and conduction of action potentials and is thus important for electrical signaling by most excitable cells. Therapeutically, the association of pain insensitivity with the loss of function of a certain sodium channel may have implications. Since Nav1.7 is not present in cardiac muscle or neurons in the central nervous system, blockers of Nav1.7 will not have direct action on these cells and thus can have less side effects than current pain medications. By performing more studies, there is a possibility to develop a new generation of drugs that can reduce the pain intensity in animals (1-3).
    基因ID
    6335
    NCBI登录号
    NP_002968
    UniProt
    Q15858
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