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Lamin A/C 抗体

This anti-Lamin A/C antibody is a 小鼠 单克隆 antibody detecting Lamin A/C in WB, IHC 和 ELISA. Suitable for 人.
Rockland
产品编号 ABIN6656055
Supplier Product No.: 200-301-x12
发货至: 中国

Quick Overview for Lamin A/C 抗体 (ABIN6656055)

抗原

See all Lamin A/C (LMNA) 抗体
Lamin A/C (LMNA)

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This Lamin A/C antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC), ELISA

克隆位点

4C4
  • Supplier Product No.

    200-301-x12

    Supplier

    Rockland

    原理

    Lamin A/C Antibody

    纯化方法

    Anti-Lamin A/C Antibody was purified from tissue culture supernatant by protein G chromatography.

    过滤

    Sterile filtered

    免疫原

    Anti-Lamin A/C Antibody was produced in mice by repeated immunizations with a recombinant full length human lamin C expressed in and purified from E. Coli.

    亚型

    IgG1
  • 应用备注

    ELISA_Dilution: 1:50,000

    Immunohistochemistry_Dilution: 1:1000

    Western_Blot_Dilution: 1:5000

    Other: ICC: 1:1000

    说明

    Anti-Lamin A/C Antibody is tested for Western Blot, Immunocytochemistry, and Immunohistochemistry, and it is specific for the ~64 and 74 kDa lamin A and C proteins. Specific conditions for reactivity should be optimized by the end user.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2

    Stabilizer: None

    Preservative: 0.01 % (w/v) Sodium Azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store vial at -20° C prior to opening in undiluted aliquots. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature.

    有效期

    12 months
  • 抗原

    Lamin A/C (LMNA)

    别名

    Lamin A/C

    背景

    Synonyms: Prelamin-A/C, 70 kDa lamin, Renal carcinoma antigen NY-REN-32, LMN1

    Background: Lamins A and C are nuclear structural proteins that are part of the intermediate filament family and coded for by the same gene (LMNA). Lamins A and C are nearly identical except for their carboxy termini. Mutations in the gene encoding lamins A/C have been shown to cause a variety of diseases including autosomal dominant Emery-Dreifuss muscular dystrophy, autosomal dominant limb-girdle muscular dystrophy and Charcot-Marie-Tooth disorder type 2. Lamin A/C Antibody is ideal for researchers interested in cancer research.

    Gene Name: LMNA

    基因ID

    4000

    UniProt

    P02545

    途径

    Apoptosis, Caspase Cascade in Apoptosis, ER-Nucleus Signaling, Protein targeting to Nucleus
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