SMARCA5 抗体
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- 抗原 See all SMARCA5 抗体
- SMARCA5 (SWI/SNF Related, Matrix Associated, Actin Dependent Regulator of Chromatin, Subfamily A, Member 5 (SMARCA5))
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This SMARCA5 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunoprecipitation (IP), Fluorescence Microscopy (FM)
- 纯化方法
- Anti-hSNF2H was clarified from mouse ascitic fluid and is specific for hSNF2H.
- 免疫原
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Immunogen: Anti-hSNF2H Antibody was produced in mice by repeated immunization with a recombinant protein of human SNF2H.
Immunogen Type: Recombinant Protein
- Top Product
- Discover our top product SMARCA5 Primary Antibody
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- 应用备注
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Application Note: Anti-hSNF2H Antibody is suitable for Immunofluorescence, Immunoprecipitation and Western Blots. Specific conditions for reactivity should be optimized by the end user. Expect a band approximately 121.9 kDa in the appropriate cell lysate or extract.
Immunoprecipitation Dilution: 1 μg/IP
Western Blot Dilution: 1:1,000
IF Microscopy Dilution: 1:100 - 1:500
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
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Stabilizer: None
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- RT,4 °C,-20 °C
- 储存方法
- Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.
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- 抗原
- SMARCA5 (SWI/SNF Related, Matrix Associated, Actin Dependent Regulator of Chromatin, Subfamily A, Member 5 (SMARCA5))
- 别名
- hSNF2H (SMARCA5 产品)
- 别名
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- 背景
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Synonyms: mouse anti-hSNF2H Antibody, mouse anti-SNF2H Antibody, mouse anti-Sucrose nonfermenting protein 2 homolog antibody, SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5, SWI/SNF-related matrix-associated actin-dependent regulator of chromatin A5, Sucrose nonfermenting protein 2 homolog
Background: Complexes containing Snf2h (SMARCA5) are capable of forming ordered nucleosome arrays on chromatin in vitro (may require intact histone H4 tails). SNF2h is also required for replication of pericentric heterochromatin in S-phase, specifically in conjunction with BAZ1A. Snf2h probably also plays a role in repression of polI dependent transcription of the rDNA locus, through the recruitment of the SIN3/HDAC1 corepressor complex to the rDNA promoter. Snf2h is a catalytic subunit of the four known chromatin-remodeling complexes: CHRAC, RSF, ACF/WCRF, and WICH. Each complex contains subunits which may regulate the specificity or catalytic activity of SMARCA5. Snf2h possesses intrinsic ATP-dependent nucleosome remodelling activity. Anti-hSNF2H Antibody is ideal for research in Chromatin Remodeling, Epigenetics and Gene Expression.
Gene Name: SMARCA5
- 基因ID
- 8467
- NCBI登录号
- NP_003592
- UniProt
- O60264
- 途径
- Chromatin Binding
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