SMARCA5 抗体 (C-Term)
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北京 101111
Quick Overview for SMARCA5 抗体 (C-Term) (ABIN6265180)
抗原
See all SMARCA5 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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特异性
- SMARCA5 Antibody detects endogenous levels of total SMARCA5.
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预测反应
- Pig,Bovine,Horse,Sheep,Rabbit,Dog
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纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
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免疫原
- A synthesized peptide derived from human SMARCA5, corresponding to a region within C-terminal amino acids.
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亚型
- IgG
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anti-SWI/SNF Related, Matrix Associated, Actin Dependent Regulator of Chromatin, Subfamily A, Member 5 (SMARCA5) antibody
SMARCA5 适用: 人 WB, IF, IP 宿主: 兔 Monoclonal unconjugated
anti-SWI/SNF Related, Matrix Associated, Actin Dependent Regulator of Chromatin, Subfamily A, Member 5 (SMARCA5) (AA 100-400) antibodySMARCA5 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-SWI/SNF Related, Matrix Associated, Actin Dependent Regulator of Chromatin, Subfamily A, Member 5 (SMARCA5) (AA 1-1052) antibodySMARCA5 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-SWI/SNF Related, Matrix Associated, Actin Dependent Regulator of Chromatin, Subfamily A, Member 5 (SMARCA5) (AA 59-147) antibodySMARCA5 适用: 人 WB, ELISA, IF, IHC (p) 宿主: 小鼠 Monoclonal 3F4 unconjugated
anti-SWI/SNF Related, Matrix Associated, Actin Dependent Regulator of Chromatin, Subfamily A, Member 5 (SMARCA5) (AA 1-1052) antibodySMARCA5 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-SWI/SNF Related, Matrix Associated, Actin Dependent Regulator of Chromatin, Subfamily A, Member 5 (SMARCA5) antibodySMARCA5 适用: 人 WB, FACS 宿主: 兔 Monoclonal 23GB4160 unconjugated Recombinant Antibody
anti-SWI/SNF Related, Matrix Associated, Actin Dependent Regulator of Chromatin, Subfamily A, Member 5 (SMARCA5) (AA 59-147) antibodySMARCA5 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-SWI/SNF Related, Matrix Associated, Actin Dependent Regulator of Chromatin, Subfamily A, Member 5 (SMARCA5) antibodySMARCA5 适用: 人, 小鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-SWI/SNF Related, Matrix Associated, Actin Dependent Regulator of Chromatin, Subfamily A, Member 5 (SMARCA5) (AA 51-100) antibodySMARCA5 适用: 人, 小鼠, 大鼠, 马, Cow, 犬, 豚鼠, 兔, Bat, 猴, Pig WB 宿主: 兔 Polyclonal unconjugated
anti-SWI/SNF Related, Matrix Associated, Actin Dependent Regulator of Chromatin, Subfamily A, Member 5 (SMARCA5) (AA 946-975), (C-Term) antibodySMARCA5 适用: 人 WB, FACS 宿主: 兔 Polyclonal RB20627 unconjugated
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应用备注
- WB 1:500-1:2000, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20 °C. Stable for 12 months from date of receipt.
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有效期
- 12 months
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- SMARCA5 (SWI/SNF Related, Matrix Associated, Actin Dependent Regulator of Chromatin, Subfamily A, Member 5 (SMARCA5))
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别名
- SMARCA5
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背景
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Description: Helicase that possesses intrinsic ATP-dependent nucleosome-remodeling activity. Complexes containing SMARCA5 are capable of forming ordered nucleosome arrays on chromatin, this may require intact histone H4 tails. Also required for replication of pericentric heterochromatin in S-phase specifically in conjunction with BAZ1A. Probably plays a role in repression of polI dependent transcription of the rDNA locus, through the recruitment of the SIN3/HDAC1 corepressor complex to the rDNA promoter. Essential component of the WICH complex, a chromatin remodeling complex that mobilizes nucleosomes and reconfigures irregular chromatin to a regular nucleosomal array structure. The WICH complex regulates the transcription of various genes, has a role in RNA polymerase I and RNA polymerase III transcription, mediates the histone H2AX phosphorylation at 'Tyr-142', and is involved in the maintenance of chromatin structures during DNA replication processes. Essential component of the NoRC (nucleolar remodeling complex) complex, a complex that mediates silencing of a fraction of rDNA by recruiting histone-modifying enzymes and DNA methyltransferases, leading to heterochromatin formation and transcriptional silencing.
Gene: SMARCA5
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分子量
- 122kDa
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基因ID
- 8467
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UniProt
- O60264
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途径
- Chromatin Binding
抗原
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