Retinoblastoma Binding Protein 8 抗体 (C-Term)
Quick Overview for Retinoblastoma Binding Protein 8 抗体 (C-Term) (ABIN657950)
抗原
See all Retinoblastoma Binding Protein 8 (RBBP8) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 763-792, C-Term
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纯化方法
- This antibody is purified through a protein A column, followed by peptide affinity purification.
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免疫原
- This RBBP8 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 763-792 amino acids from the C-terminal region of human RBBP8.
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亚型
- Ig Fraction
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应用备注
- WB: 1:2000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- RBBP8 Antibody (C-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the at -20 °C.
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有效期
- 6 months
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- Retinoblastoma Binding Protein 8 (RBBP8)
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别名
- RBBP8
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背景
- The protein encoded by this gene is a ubiquitously expressed nuclear protein. It is found among several proteins that bind directly to retinoblastoma protein, which regulates cell proliferation. This protein complexes with transcriptional co-repressor CTBP. It is also associated with BRCA1 and is thought to modulate the functions of BRCA1 in transcriptional regulation, DNA repair, and/or cell cycle checkpoint control. It is suggested that this gene may itself be a tumor suppressor acting in the same pathway as BRCA1. Three transcript variants encoding two different isoforms have been found for this gene. More transcript variants exist, but their full-length natures have not been determined.
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分子量
- 101942
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基因ID
- 5932
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NCBI登录号
- NP_002885, NP_976036, NP_976037
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UniProt
- Q99708
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途径
- Cell Division Cycle, DNA Damage Repair
抗原
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