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TNF alpha 抗体 (C-Term)

TNF alpha 适用: 人 WB, FACS 宿主: 兔 Polyclonal RB33595 unconjugated
产品编号 ABIN657455
发货至: 中国
  • 抗原 See all TNF alpha 抗体
    TNF alpha (Tumor Necrosis Factor alpha (TNF alpha))
    抗原表位
    • 45
    • 33
    • 15
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    • 10
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    • 1
    • 1
    • 1
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    AA 187-216, C-Term
    适用
    • 331
    • 195
    • 122
    • 64
    • 50
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    • 34
    • 26
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    宿主
    • 269
    • 194
    • 31
    • 24
    • 7
    • 6
    • 2
    • 2
    • 1
    克隆类型
    • 284
    • 246
    多克隆
    标记
    • 260
    • 78
    • 45
    • 21
    • 15
    • 11
    • 6
    • 6
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    • 1
    This TNF alpha antibody is un-conjugated
    应用范围
    • 346
    • 211
    • 134
    • 121
    • 74
    • 57
    • 53
    • 48
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    • 42
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    • 1
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    • 1
    • 1
    Western Blotting (WB), Flow Cytometry (FACS)
    纯化方法
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    免疫原
    This TNF antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 187-216 amino acids from the C-terminal region of human TNF.
    克隆位点
    RB33595
    亚型
    Ig Fraction
    Top Product
    Discover our top product TNF alpha Primary Antibody
  • 应用备注
    WB: 1:1000. FC: 1:10~50
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    TNF Antibody (C-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the at -20 °C.
    有效期
    6 months
  • Huang, Zhao, Yu, Yang, Ding: "Protective Effects and Mechanism of Meretrix meretrix Oligopeptides against Nonalcoholic Fatty Liver Disease." in: Marine drugs, Vol. 15, Issue 2, (2017) (PubMed).

  • 抗原
    TNF alpha (Tumor Necrosis Factor alpha (TNF alpha))
    别名
    TNF (TNF alpha 产品)
    背景
    This gene encodes a multifunctional proinflammatory cytokine that belongs to the tumor necrosis factor (TNF) superfamily. This cytokine is mainly secreted by macrophages. It can bind to, and thus functions through its receptors TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. This cytokine is involved in the regulation of a wide spectrum of biological processes including cell proliferation, differentiation, apoptosis, lipid metabolism, and coagulation. This cytokine has been implicated in a variety of diseases, including autoimmune diseases, insulin resistance, and cancer. Knockout studies in mice also suggested the neuroprotective function of this cytokine.
    分子量
    25644
    基因ID
    7124
    NCBI登录号
    NP_000585
    UniProt
    P01375
    途径
    NF-kappaB Signaling, Apoptosis, Caspase Cascade in Apoptosis, TLR signaling, Cellular Response to Molecule of Bacterial Origin, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Positive Regulation of Endopeptidase Activity, Hepatitis C, Protein targeting to Nucleus, Inflammasome
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