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SIRPA 抗体

SIRPA 适用: 人, 小鼠, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN5965376
发货至: 中国
  • 抗原 See all SIRPA 抗体
    SIRPA (Signal-Regulatory Protein alpha (SIRPA))
    适用
    • 70
    • 38
    • 32
    • 9
    • 8
    • 4
    • 3
    • 3
    人, 小鼠, 大鼠
    宿主
    • 56
    • 33
    • 1
    克隆类型
    • 55
    • 35
    多克隆
    标记
    • 44
    • 11
    • 6
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This SIRPA antibody is un-conjugated
    应用范围
    • 55
    • 46
    • 19
    • 18
    • 12
    • 11
    • 11
    • 9
    • 9
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB)
    纯化方法
    Affinity purification
    免疫原
    Recombinant protein of human SIRPA
    亚型
    IgG
    Top Product
    Discover our top product SIRPA Primary Antibody
  • 应用备注
    WB 1:200 - 1:2000
    限制
    仅限研究用
  • 浓度
    1 mg/mL
    缓冲液
    Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原
    SIRPA (Signal-Regulatory Protein alpha (SIRPA))
    别名
    SIRPA (SIRPA 产品)
    别名
    BIT antibody, CD172A antibody, MFR antibody, MYD-1 antibody, P84 antibody, PTPNS1 antibody, SHPS1 antibody, SIRP antibody, SIRPA antibody, SIRP-A1 antibody, SIRP-B1 antibody, AI835480 antibody, Bit antibody, CD172a antibody, Ptpns1 antibody, SHP-1 antibody, SHPS-1 antibody, swc3 antibody, signal regulatory protein alpha antibody, myeloperoxidase antibody, signal-regulatory protein alpha antibody, tyrosine-protein phosphatase non-receptor type substrate 1 antibody, SIRPA antibody, MPO antibody, LOC458039 antibody, LOC100400378 antibody, LOC100590224 antibody, Sirpa antibody
    背景

    Synonyms: Signal regulatory protein alpha type 1,Bit,Brain Ig like molecule with tyrosine based activation motifs,Brain Ig-like molecule with tyrosine-based activation motifs,Brain immunoglobulin like molecule with tyrosine based activation motifs,CD172 antigen like family member A,CD172 antigen-like family member A,CD172a,CD172a antigen,Inhibitory receptor SHPS-1,Macrophage fusion receptor,MFR,MYD 1,Myd 1 antigen,MyD-1 antigen,p84,Protein tyrosine phosphatase non receptor type substrate 1,PTPNS1,SHP substrate 1,SHPS-1,SHPS1,SHPS1,Signal regulatory protein alpha 2,Signal regulatory protein alpha 3,Signal regulatory protein alpha,Signal regulatory protein alpha type 2,Signal-regulatory protein alpha-1,Signal-regulatory protein alpha-2,Signal-regulatory protein alpha-3,SIRP,Sirp-alpha-1,Sirp-alpha-2,Sirp-alpha-3,SIRPA,SIRPalpha,SIRPalpha1,SIRPalpha2,SIRPalpha3,Tyrosine phosphatase SHP substrate 1,Tyrosine protein phosphatase non receptor type substrate 1,Tyrosine-protein phosphatase non-receptor type substrate 1

    Background: The protein encoded by this gene is a member of the signal-regulatory-protein (SIRP) family, and also belongs to the immunoglobulin superfamily. SIRP family members are receptor-type transmembrane glycoproteins known to be involved in the negative regulation of receptor tyrosine kinase-coupled signaling processes. This protein can be phosphorylated by tyrosine kinases. The phospho-tyrosine residues of this PTP have been shown to recruit SH2 domain containing tyrosine phosphatases (PTP), and serve as substrates of PTPs. This protein was found to participate in signal transduction mediated by various growth factor receptors. CD47 has been demonstrated to be a ligand for this receptor protein. This gene and its product share very high similarity with several other members of the SIRP family. These related genes are located in close proximity to each other on chromosome 20p13. Multiple alternatively spliced transcript variants have been determined for this gene.

    分子量

    Observed_MW: 120kDa

    Calculated_MW: 54kDa/55kDa

    基因ID
    140885
    UniProt
    P78324
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