CDC45 抗体
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- 抗原 See all CDC45 抗体
- CDC45 (Cell Division Cycle 45 Homolog (S. Cerevisiae) (CDC45))
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This CDC45 antibody is un-conjugated
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应用范围
- Immunohistochemistry (IHC)
- 纯化方法
- Affinity purification
- 免疫原
- Recombinant fusion protein of human CDC45 (NP_003495.1).
- 亚型
- IgG
- Top Product
- Discover our top product CDC45 Primary Antibody
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- 应用备注
- IHC 1:50-1:200
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- 抗原
- CDC45 (Cell Division Cycle 45 Homolog (S. Cerevisiae) (CDC45))
- 别名
- CDC45 (CDC45 产品)
- 别名
- cdc45l antibody, cdc45l2 antibody, porc-pi-1 antibody, CDC45L antibody, CDC45L2 antibody, PORC-PI-1 antibody, Cdc45l antibody, cell division cycle 45 antibody, cell division cycle 45 S homeolog antibody, cell division cycle 45 L homeolog antibody, cdc45 antibody, CDC45 antibody, cdc45.S antibody, Cdc45 antibody, cdc45.L antibody
- 背景
- The protein encoded by this gene was identified by its strong similarity with Saccharomyces cerevisiae Cdc45, an essential protein required to the initiation of DNA replication. Cdc45 is a member of the highly conserved multiprotein complex including Cdc6/Cdc18, the minichromosome maintenance proteins (MCMs) and DNA polymerase, which is important for early steps of DNA replication in eukaryotes. This protein has been shown to interact with MCM7 and DNA polymerase alpha. Studies of the similar gene in Xenopus suggested that this protein play a pivotal role in the loading of DNA polymerase alpha onto chromatin. Alternate splicing results in multiple transcript variants.
- 分子量
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Observed_MW: 60kDa
Calculated_MW: 60kDa/65kDa/68kDa
- 基因ID
- 8318
- UniProt
- O75419
- 途径
- Mitotic G1-G1/S Phases, DNA Replication, Synthesis of DNA
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