CDC45 抗体
(Cell Division Cycle 45 Homolog (S. Cerevisiae) (CDC45))
The protein encoded by this gene was identified by its strong similarity with Saccharomyces cerevisiae Cdc45, an essential protein required to the initiation of DNA replication. Cdc45 is a member of the highly conserved multiprotein complex including Cdc6/Cdc18, the minichromosome maintenance proteins (MCMs) and DNA polymerase, which is important for early steps of DNA replication in eukaryotes. This protein has been shown to interact with MCM7 and DNA polymerase alpha. Studies of the similar gene in Xenopus suggested that this protein play a pivotal role in the loading of DNA polymerase alpha onto chromatin. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2010].
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CDC45
适用: 小鼠, 大鼠
IF (cc), IF (p)
宿主: 兔
Polyclonal
AbBy Fluor® 680
CDC45
适用: 小鼠, 大鼠
IF (cc), IF (p)
宿主: 兔
Polyclonal
AbBy Fluor® 750
Latest Publications for our CDC45 抗体
: "A nontranscriptional role for HIF-1α as a direct inhibitor of DNA replication." in: Science signaling, Vol. 6, Issue 262, pp. ra10, (2013) (PubMed).
Aliases for CDC45 抗体
cell division cycle 45 (cdc45) 抗体cell division cycle 45 (CDC45) 抗体
cell division cycle 45 S homeolog (cdc45.S) 抗体
cell division cycle 45 (Cdc45) 抗体
cell division cycle 45 L homeolog (cdc45.L) 抗体
cdc45l 抗体
CDC45L 抗体
Cdc45l 抗体
cdc45l2 抗体
CDC45L2 抗体
porc-pi-1 抗体
PORC-PI-1 抗体
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