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Importin 5 抗体

IPO5 适用: 人, 小鼠 WB, IF 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN6569027
发货至: 中国
  • 抗原 See all Importin 5 (IPO5) 抗体
    Importin 5 (IPO5)
    适用
    • 27
    • 26
    • 12
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    人, 小鼠
    宿主
    • 38
    • 4
    克隆类型
    • 40
    • 2
    多克隆
    标记
    • 14
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This Importin 5 antibody is un-conjugated
    应用范围
    • 13
    • 13
    • 12
    • 7
    • 6
    • 5
    • 3
    • 3
    • 2
    • 1
    Western Blotting (WB), Immunofluorescence (IF)
    纯化方法
    Affinity purification
    免疫原
    Recombinant fusion protein of human IPO5 (NP_002262.3).
    亚型
    IgG
    Top Product
    Discover our top product IPO5 Primary Antibody
  • 应用备注
    WB 1:500-1:2000 IF 1:50-1:200
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原
    Importin 5 (IPO5)
    别名
    IPO5 (IPO5 产品)
    别名
    IPO5 antibody, RANBP5 antibody, IMB3 antibody, KPNB3 antibody, Pse1 antibody, imp5 antibody, 1110011C18Rik antibody, 5730478E03Rik antibody, AA409333 antibody, C76941 antibody, Kpnb3 antibody, Ranbp5 antibody, importin 5 antibody, IPO5 antibody, Ipo5 antibody
    背景
    Nucleocytoplasmic transport, a signal- and energy-dependent process, takes place through nuclear pore complexes embedded in the nuclear envelope. The import of proteins containing a nuclear localization signal (NLS) requires the NLS import receptor, a heterodimer of importin alpha and beta subunits also known as karyopherins. Importin alpha binds the NLS-containing cargo in the cytoplasm and importin beta docks the complex at the cytoplasmic side of the nuclear pore complex. In the presence of nucleoside triphosphates and the small GTP binding protein Ran, the complex moves into the nuclear pore complex and the importin subunits dissociate. Importin alpha enters the nucleoplasm with its passenger protein and importin beta remains at the pore. Interactions between importin beta and the FG repeats of nucleoporins are essential in translocation through the pore complex. The protein encoded by this gene is a member of the importin beta family.
    分子量

    Observed_MW: 125kDa

    Calculated_MW: 116kDa/123kDa/125kDa

    基因ID
    3843
    UniProt
    O00410
    途径
    Protein targeting to Nucleus
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