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Importin 5 产品

(Importin 5 (IPO5))

Categories

Nucleocytoplasmic transport, a signal- and energy-dependent process, takes place through nuclear pore complexes embedded in the nuclear envelope. The import of proteins containing a nuclear localization signal (NLS) requires the NLS import receptor, a heterodimer of importin alpha and beta subunits also known as karyopherins. Importin alpha binds the NLS-containing cargo in the cytoplasm and importin beta docks the complex at the cytoplasmic side of the nuclear pore complex. In the presence of nucleoside triphosphates and the small GTP binding protein Ran, the complex moves into the nuclear pore complex and the importin subunits dissociate. Importin alpha enters the nucleoplasm with its passenger protein and importin beta remains at the pore. Interactions between importin beta and the FG repeats of nucleoporins are essential in translocation through the pore complex. The protein encoded by this gene is a member of the importin beta family. [provided by RefSeq, Jul 2008].

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Featured Importin 5 Categories

Importin 5 抗体

High quality antibodies with extensive validation data.

Importin 5 蛋白

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended Importin 5 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, ELISA, IHC (p)
Validations
  • (2)
  • (7)
Cat. No. ABIN561620
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB
Validations
  • (5)
Cat. No. ABIN3015798
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IF
Validations
  • (4)
Cat. No. ABIN517375
Quantity 50 μg
Datasheet Datasheet

Recommended Importin 5 蛋白

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1308015
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3093212
Quantity 1 mg
Datasheet Datasheet
Reactivity Mouse
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3136198
Quantity 1 mg
Datasheet Datasheet

Latest Publications for our Importin 5 Products

Song, Lee, Kim, Lee, Chang, Lee: "Fas-Associated Factor 1 Negatively Regulates the Antiviral Immune Response by Inhibiting Translocation of Interferon Regulatory Factor 3 to the Nucleus." in: Molecular and cellular biology, Vol. 36, Issue 7, pp. 1136-51, (2016) (PubMed).

Hurd, Fan, Margolis: "Localization of retinitis pigmentosa 2 to cilia is regulated by Importin beta2." in: Journal of cell science, Vol. 124, Issue Pt 5, pp. 718-26, (2011) (PubMed).

Synonyms and alternative names related to Importin 5

importin 5 (IPO5), importin 5 (Ipo5), 1110011C18Rik, 5730478E03Rik, AA409333, C76941, IMB3, imp5, IPO5, KPNB3, Kpnb3, Pse1, RANBP5, Ranbp5

Protein level used designations for Importin 5

  • importin 5
  • RAN binding protein 5
  • Ran_GTP binding protein 5
  • importin beta-3 subunit
  • importin subunit beta-3
  • importin-5
  • karyopherin (importin) beta 3
  • karyopherin beta-3
  • ran-binding protein 5
  • imp5
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