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BIM 抗体

BCL2L11 适用: 人 IHC, IF 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN5966248
发货至: 中国
  • 抗原 See all BIM (BCL2L11) 抗体
    BIM (BCL2L11) (BCL2-Like 11 (Apoptosis Facilitator) (BCL2L11))
    适用
    • 155
    • 98
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    • 5
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    宿主
    • 144
    • 8
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    克隆类型
    • 131
    • 25
    多克隆
    标记
    • 63
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    This BIM antibody is un-conjugated
    应用范围
    • 98
    • 52
    • 45
    • 19
    • 18
    • 14
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    • 12
    • 10
    • 10
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    Immunohistochemistry (IHC), Immunofluorescence (IF)
    纯化方法
    Affinity purification
    免疫原
    Recombinant fusion protein of human Bim (NP_619527.1).
    亚型
    IgG
    Top Product
    Discover our top product BCL2L11 Primary Antibody
  • 应用备注
    IHC 1:50-1:100 IF 1:50-1:100
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原
    BIM (BCL2L11) (BCL2-Like 11 (Apoptosis Facilitator) (BCL2L11))
    别名
    Bim (BCL2L11 产品)
    别名
    bim antibody, BAM antibody, BIM antibody, BOD antibody, 1500006F24Rik antibody, Bim antibody, Bod antibody, BimL antibody, BIMEL antibody, BCL2-like 11 antibody, BCL2 like 11 antibody, BCL2-like 11 (apoptosis facilitator) antibody, bcl2l11 antibody, BCL2L11 antibody, Bcl2l11 antibody
    背景
    The protein encoded by this gene belongs to the BCL-2 protein family. BCL-2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. The protein encoded by this gene contains a Bcl-2 homology domain 3 (BH3). It has been shown to interact with other members of the BCL-2 protein family and to act as an apoptotic activator. The expression of this gene can be induced by nerve growth factor (NGF), as well as by the forkhead transcription factor FKHR-L1, which suggests a role of this gene in neuronal and lymphocyte apoptosis. Transgenic studies of the mouse counterpart suggested that this gene functions as an essential initiator of apoptosis in thymocyte-negative selection. Several alternatively spliced transcript variants of this gene have been identified.
    分子量

    Calculated_MW: 4-22kDa

    基因ID
    10018
    UniProt
    O43521
    途径
    PI3K-Akt Signaling, Neurotrophin Signaling Pathway, Tube Formation, Positive Regulation of Endopeptidase Activity
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