BIM 抗体
(BCL2-Like 11 (Apoptosis Facilitator) (BCL2L11))
The protein encoded by this gene belongs to the BCL-2 protein family. BCL-2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. The protein encoded by this gene contains a Bcl-2 homology domain 3 (BH3). It has been shown to interact with other members of the BCL-2 protein family, including BCL2, BCL2L1/BCL-X(L), and MCL1, and to act as an apoptotic activator. The expression of this gene can be induced by nerve growth factor (NGF), as well as by the forkhead transcription factor FKHR-L1, which suggests a role of this gene in neuronal and lymphocyte apoptosis. Transgenic studies of the mouse counterpart suggested that this gene functions as an essential initiator of apoptosis in thymocyte-negative selection. Several alternatively spliced transcript variants of this gene have been identified. [provided by RefSeq, Jul 2008].
| Catalog no. | 产品 | 适用 | 宿主 / 克隆类型 | 应用 | 价格和交货时间 |
|---|---|---|---|---|---|
| BIM 抗体 (AA 2-120) | 人 | 兔 Polyclonal |
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| BIM 抗体 (AA 134-160) | 人 | 兔 Polyclonal |
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| BIM 抗体 (pSer87) | 人 | 兔 Polyclonal |
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|
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| BIM 抗体 (AA 130-165) | 人 | 兔 Polyclonal |
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|
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| BIM 抗体 (AA 1-198) | 人 | 兔 Polyclonal |
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|
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| Recombinant BIM 抗体 | 人 | 兔 Monoclonal |
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| BIM 抗体 (C-Term) | 人, 小鼠 | 兔 Polyclonal |
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|
|
| BIM 抗体 (AA 51-150) | 人 | 兔 Polyclonal |
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| BIM 抗体 (pSer77) | 人, 小鼠, 大鼠 | 兔 Polyclonal |
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| BIM 抗体 (pSer69) | 人 | 兔 Polyclonal |
|
|
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| BIM 抗体 (Middle Region) | 人 | 兔 Polyclonal |
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|
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| BIM 抗体 (N-Term) | 人, 小鼠, 大鼠, 猴 | 兔 Polyclonal |
|
|
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| BIM 抗体 (AA 2-198) | 人, 小鼠 | 小鼠 Monoclonal |
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|
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| BIM 抗体 (AA 1-100) | 人 | 小鼠 Monoclonal |
|
|
|
| BIM 抗体 (C-Term) | 人 | 山羊 Polyclonal |
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|
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| BIM 抗体 (pSer69) | 人, 小鼠, 大鼠, Cow, 绵羊 | 兔 Polyclonal |
|
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| BIM 抗体 (AA 130-165) | 人 | 兔 Polyclonal |
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|
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| BIM 抗体 (pSer87) (HRP) | 人 | 兔 Polyclonal |
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| BIM 抗体 (pSer87) (Cy3) | 人 | 兔 Polyclonal |
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| BIM 抗体 (pSer87) (AbBy Fluor® 350) | 人 | 兔 Polyclonal |
|
|
Primary Antibody
- WB (Western Blotting: 有验证图片)
- IHC (Immunohistochemistry: 有验证图片)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗体亚型
- IgG
- 抗原表位
- AA 2-120
Primary Antibody
- WB (Western Blotting: 有验证图片)
- FACS (Flow Cytometry: 有验证图片)
- IHC (p) (Immunohistochemistry (Paraffin-embedded Sections): 有验证图片)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 克隆
- RB22105
- 标记
- unconjugated
- 抗体亚型
- Ig Fraction
- 抗原表位
- AA 134-160
Primary Antibody
- IHC (p) (Immunohistochemistry (Paraffin-embedded Sections): 有验证图片)
- IHC (Immunohistochemistry: 有验证图片)
- WB (Western Blotting: 所列应用)
- IF (cc) (Immunofluorescence (Cultured Cells): 所列应用)
- IF (p) (Immunofluorescence (Paraffin-embedded Sections): 所列应用)
- IHC (fro) (Immunohistochemistry (Frozen Sections): 所列应用)
2 references - 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗体亚型
- IgG
- 抗原表位
- pSer87
Primary Antibody
- WB (Western Blotting: 有验证图片)
- IHC (p) (Immunohistochemistry (Paraffin-embedded Sections): 有验证图片)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 克隆
- RB00963
- 标记
- unconjugated
- 抗体亚型
- Ig Fraction
- 抗原表位
- AA 130-165
Primary Antibody
- IHC (Immunohistochemistry: 有验证图片)
- IF (Immunofluorescence: 有验证图片)
- ICC (Immunocytochemistry: 有验证图片)
- ELISA (ELISA: 所列应用)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗体亚型
- IgG
- 抗原表位
- AA 1-198
Primary Antibody
- WB (Western Blotting: 有验证图片)
- FACS (Flow Cytometry: 有验证图片)
KO 验证
- 质量等级
- KO Validated
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Monoclonal
- 克隆
- 25GB610
- 标记
- unconjugated
- 蛋白类型
- Recombinant Antibody
- 抗体亚型
- IgG
Primary Antibody
- WB (Western Blotting: 有验证图片)
- IHC (Immunohistochemistry: 有验证图片)
- FACS (Flow Cytometry: 有验证图片)
- 适用
- 人, 小鼠
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗体亚型
- IgG
- 抗原表位
- C-Term
Primary Antibody
- WB (Western Blotting: 有验证图片)
- IHC (Immunohistochemistry: 有验证图片)
- FACS (Flow Cytometry: 所列应用)
- IHC (p) (Immunohistochemistry (Paraffin-embedded Sections): 所列应用)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗体亚型
- IgG
- 抗原表位
- AA 51-150
Primary Antibody
- WB (Western Blotting: 有验证图片)
- IHC (p) (Immunohistochemistry (Paraffin-embedded Sections): 有验证图片)
- IHC (Immunohistochemistry: 所列应用)
- 适用
- 人, 小鼠, 大鼠
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗体亚型
- IgG
- 抗原表位
- pSer77
Primary Antibody
- IHC (Immunohistochemistry: 有验证图片)
- IF (Immunofluorescence: 有验证图片)
- ELISA (ELISA: 所列应用)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗体亚型
- IgG
- 抗原表位
- pSer69
Primary Antibody
- WB (Western Blotting: 有验证图片)
- IHC (p) (Immunohistochemistry (Paraffin-embedded Sections): 有验证图片)
- FACS (Flow Cytometry: 有验证图片)
- EIA (Enzyme Immunoassay: 所列应用)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗原表位
- Middle Region
Primary Antibody
- WB (Western Blotting: 有验证图片)
- IHC (Immunohistochemistry: 所列应用)
- ELISA (ELISA: 所列应用)
- 适用
- 人, 小鼠, 大鼠, 猴
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗体亚型
- IgG
- 抗原表位
- N-Term
Primary Antibody
- WB (Western Blotting: 所列应用)
- IHC (Immunohistochemistry: 所列应用)
- ELISA (ELISA: 所列应用)
- IHC (p) (Immunohistochemistry (Paraffin-embedded Sections): 所列应用)
- 适用
- 人, 小鼠
- 宿主
- 小鼠
- 克隆形成能力
- Monoclonal
- 克隆
- 1C2C8
- 标记
- unconjugated
- 抗体亚型
- IgG1
- 抗原表位
- AA 2-198
Primary Antibody
- ELISA (ELISA: 有验证图片)
- 适用
- 人
- 宿主
- 小鼠
- 克隆形成能力
- Monoclonal
- 克隆
- 2F10
- 标记
- unconjugated
- 抗体亚型
- IgG1
- 抗原表位
- AA 1-100
Primary Antibody
- WB (Western Blotting: 有验证图片)
- ELISA (ELISA: 所列应用)
- 质量等级
- Verified
- 适用
- 人
- 宿主
- 山羊
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗体亚型
- IgG
- 抗原表位
- C-Term
Primary Antibody
- WB (Western Blotting: 有验证图片)
- IHC (Immunohistochemistry: 有验证图片)
- IF (Immunofluorescence: 有验证图片)
- 适用
- 人, 小鼠, 大鼠, Cow, 绵羊
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗原表位
- pSer69
Primary Antibody
- WB (Western Blotting: 有验证图片)
- IHC (Immunohistochemistry: 有验证图片)
- ELISA (ELISA: 所列应用)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗体亚型
- Ig Fraction
- 抗原表位
- AA 130-165
Primary Antibody
- WB (Western Blotting: 所列应用)
- IHC (p) (Immunohistochemistry (Paraffin-embedded Sections): 所列应用)
- IHC (fro) (Immunohistochemistry (Frozen Sections): 所列应用)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- HRP
- 抗体亚型
- IgG
- 抗原表位
- pSer87
Primary Antibody
- WB (Western Blotting: 所列应用)
- IF (cc) (Immunofluorescence (Cultured Cells): 所列应用)
- IF (p) (Immunofluorescence (Paraffin-embedded Sections): 所列应用)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- Cy3
- 抗体亚型
- IgG
- 抗原表位
- pSer87
Primary Antibody
- WB (Western Blotting: 所列应用)
- IF (cc) (Immunofluorescence (Cultured Cells): 所列应用)
- IF (p) (Immunofluorescence (Paraffin-embedded Sections): 所列应用)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- AbBy Fluor® 350
- 抗体亚型
- IgG
- 抗原表位
- pSer87
Latest Publications for our BIM 抗体
: "Functional disparities among BCL-2 members in tonsillar and leukemic B-cell subsets assessed by BH3-mimetic profiling." in: Cell death and differentiation, Vol. 24, Issue 1, pp. 111-119, (2018) (PubMed).
: "Role of Sirtuin3 in high glucose-induced apoptosis in renal tubular epithelial cells." in: Biochemical and biophysical research communications, Vol. 480, Issue 3, pp. 387-393, (2017) (PubMed).
: "RIPK1 regulates survival of human melanoma cells upon endoplasmic reticulum stress through autophagy." in: Autophagy, Vol. 11, Issue 7, pp. 975-94, (2015) (PubMed).
: "Apoptosis induced by Ginkgo biloba (EGb761) in melanoma cells is Mcl-1-dependent." in: PLoS ONE, Vol. 10, Issue 4, pp. e0124812, (2015) (PubMed).
: "Valproic acid protects motor neuron death by inhibiting oxidative stress and endoplasmic reticulum stress-mediated cytochrome C release after spinal cord injury." in: Journal of neurotrauma, Vol. 31, Issue 6, pp. 582-94, (2014) (PubMed).
: "Bim, a proapoptotic protein, up-regulated via transcription factor E2F1-dependent mechanism, functions as a prosurvival molecule in cancer." in: The Journal of biological chemistry, Vol. 288, Issue 1, pp. 368-81, (2013) (PubMed).
: "OBATOCLAX and ABT-737 induce ER stress responses in human melanoma cells that limit induction of apoptosis." in: PLoS ONE, Vol. 8, Issue 12, pp. e84073, (2013) (PubMed).
: "Loss of the Birt-Hogg-Dubé tumor suppressor results in apoptotic resistance due to aberrant TGFβ-mediated transcription." in: Oncogene, Vol. 30, Issue 22, pp. 2534-46, (2011) (PubMed).
: "Hepatic effects among workers exposed to ethylene glycol monoethyl ether acetate." in: Industrial health, Vol. 46, Issue 5, pp. 463-9, (2008) (PubMed).
: "BCL-2 dependence and ABT-737 sensitivity in acute lymphoblastic leukemia." in: Blood, Vol. 111, Issue 4, pp. 2300-9, (2008) (PubMed).
: "Role of Sirtuin3 in high glucose-induced apoptosis in renal tubular epithelial cells." in: Biochemical and biophysical research communications, Vol. 480, Issue 3, pp. 387-393, (2017) (PubMed).
: "RIPK1 regulates survival of human melanoma cells upon endoplasmic reticulum stress through autophagy." in: Autophagy, Vol. 11, Issue 7, pp. 975-94, (2015) (PubMed).
: "Apoptosis induced by Ginkgo biloba (EGb761) in melanoma cells is Mcl-1-dependent." in: PLoS ONE, Vol. 10, Issue 4, pp. e0124812, (2015) (PubMed).
: "Valproic acid protects motor neuron death by inhibiting oxidative stress and endoplasmic reticulum stress-mediated cytochrome C release after spinal cord injury." in: Journal of neurotrauma, Vol. 31, Issue 6, pp. 582-94, (2014) (PubMed).
: "Bim, a proapoptotic protein, up-regulated via transcription factor E2F1-dependent mechanism, functions as a prosurvival molecule in cancer." in: The Journal of biological chemistry, Vol. 288, Issue 1, pp. 368-81, (2013) (PubMed).
: "OBATOCLAX and ABT-737 induce ER stress responses in human melanoma cells that limit induction of apoptosis." in: PLoS ONE, Vol. 8, Issue 12, pp. e84073, (2013) (PubMed).
: "Loss of the Birt-Hogg-Dubé tumor suppressor results in apoptotic resistance due to aberrant TGFβ-mediated transcription." in: Oncogene, Vol. 30, Issue 22, pp. 2534-46, (2011) (PubMed).
: "Hepatic effects among workers exposed to ethylene glycol monoethyl ether acetate." in: Industrial health, Vol. 46, Issue 5, pp. 463-9, (2008) (PubMed).
: "BCL-2 dependence and ABT-737 sensitivity in acute lymphoblastic leukemia." in: Blood, Vol. 111, Issue 4, pp. 2300-9, (2008) (PubMed).
Aliases for BIM 抗体
BCL2-like 11 (bcl2l11) 抗体BCL2 like 11 (BCL2L11) 抗体
BCL2-like 11 (apoptosis facilitator) (Bcl2l11) 抗体
BCL2 like 11 (Bcl2l11) 抗体
1500006F24Rik 抗体
BAM 抗体
bim 抗体
BIM 抗体
Bim 抗体
BIMEL 抗体
BimL 抗体
BOD 抗体
Bod 抗体
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