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BIM 抗体 (pSer77)

The 兔 多克隆 anti-BIM antibody (ABIN6255502) specifically detects BIM in WB 和 IHC. The antibody is reactive with 人, 小鼠 和 大鼠 samples.
产品编号 ABIN6255502
发货至: 中国
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Quick Overview for BIM 抗体 (pSer77) (ABIN6255502)

抗原

See all BIM (BCL2L11) 抗体
BIM (BCL2L11) (BCL2-Like 11 (Apoptosis Facilitator) (BCL2L11))

适用

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人, 小鼠, 大鼠

宿主

  • 144
  • 7
  • 3
  • 1

克隆类型

  • 119
  • 36
多克隆

标记

  • 74
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This BIM antibody is un-conjugated

应用范围

  • 101
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Western Blotting (WB), Immunohistochemistry (IHC)
  • 抗原表位

    • 15
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    pSer77

    特异性

    Phospho-Bim (Ser77) Antibody detects endogenous levels of Bim.

    交叉反应

    人, 小鼠, 大鼠

    纯化方法

    The antibody is from purified rabbit serum by affinity purification via sequential chromatography on phospho- and non-phospho-peptide affinity columns.

    免疫原

    A synthesized peptide derived from human Bim around the phosphorylation site of Ser77.

    亚型

    IgG
  • 应用备注

    WB 1:500-1:2000, IHC 1:50-1:200

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    Rabbit IgG in phosphate buffered saline ,  pH 7.4, 150  mM NaCl, 0.02 % sodium azide and 50 % glycerol.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20 °C.Stable for 12 months from date of receipt

    有效期

    12 months
  • 抗原

    BIM (BCL2L11) (BCL2-Like 11 (Apoptosis Facilitator) (BCL2L11))

    别名

    Bim

    背景

    Description: Induces apoptosis and anoikis. Isoform BimL is more potent than isoform BimEL. Isoform Bim-alpha1, isoform Bim-alpha2 and isoform Bim-alpha3 induce apoptosis, although less potent than isoform BimEL, isoform BimL and isoform BimS. Isoform Bim-gamma induces apoptosis. Isoform Bim-alpha3 induces apoptosis possibly through a caspase-mediated pathway. Isoform BimAC and isoform BimABC lack the ability to induce apoptosis.

    Gene: BCL2L11

    分子量

    26kDa

    基因ID

    10018

    UniProt

    O43521

    途径

    PI3K-Akt Signaling, Neurotrophin Signaling Pathway, Tube Formation, Positive Regulation of Endopeptidase Activity
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