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- 抗原 See all MLL/KMT2A (MLL) 抗体
- MLL/KMT2A (MLL) (Myeloid/lymphoid Or Mixed-Lineage Leukemia (MLL))
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This MLL/KMT2A antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 纯化方法
- Affinity purification
- 免疫原
- Recombinant protein of human KMT2A
- 亚型
- IgG
- Top Product
- Discover our top product MLL Primary Antibody
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anti-Myeloid/lymphoid Or Mixed-Lineage Leukemia (MLL) (AA 3850-3900) antibody
MLL 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Myeloid/lymphoid Or Mixed-Lineage Leukemia (MLL) (AA 3751-3968) antibodyMLL 适用: 人 WB, ELISA, IHC 宿主: 小鼠 Monoclonal 10F8D7 unconjugated
anti-Myeloid/lymphoid Or Mixed-Lineage Leukemia (MLL) (AA 801-956) antibodyMLL 适用: 人 WB, ELISA, IHC, FACS, ICC, Neut 宿主: 小鼠 Monoclonal 4A5A12 unconjugated
anti-Myeloid/lymphoid Or Mixed-Lineage Leukemia (MLL) (AA 312-343) antibodyMLL 适用: 人 IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Myeloid/lymphoid Or Mixed-Lineage Leukemia (MLL) (AA 2829-2883) antibodyMLL 适用: 人, 小鼠 WB, ChIP, ICC, ChIP-seq, IF 宿主: 兔 Polyclonal unconjugated
anti-Myeloid/lymphoid Or Mixed-Lineage Leukemia (MLL) (AA 3561-3670) antibodyMLL 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Myeloid/lymphoid Or Mixed-Lineage Leukemia (MLL) (AA 3879-3908), (C-Term) antibodyMLL 适用: 人 IHC (p), FACS 宿主: 兔 Polyclonal RB02951 unconjugated
anti-Myeloid/lymphoid Or Mixed-Lineage Leukemia (MLL) (C-Term) antibodyMLL 适用: 人 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
anti-Myeloid/lymphoid Or Mixed-Lineage Leukemia (MLL) antibodyMLL 适用: 人 IHC, FACS 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- WB 1:500 - 1:2000
- 限制
- 仅限研究用
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- 浓度
- 1 mg/mL
- 缓冲液
- Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- 抗原
- MLL/KMT2A (MLL) (Myeloid/lymphoid Or Mixed-Lineage Leukemia (MLL))
- 别名
- KMT2A (MLL 产品)
- 别名
- ALL-1 antibody, CXXC7 antibody, HRX antibody, HTRX1 antibody, MLL antibody, MLL/GAS7 antibody, MLL1A antibody, TET1-MLL antibody, TRX1 antibody, WDSTS antibody, 6430520K01 antibody, All1 antibody, Cxxc7 antibody, Mll antibody, Mll1 antibody, mKIAA4050 antibody, lysine methyltransferase 2A antibody, lysine (K)-specific methyltransferase 2A antibody, KMT2A antibody, Kmt2a antibody
- 背景
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Synonyms: ALL-1,ALL1,C-terminal cleavage product of 180 kDa,CXXC-type zinc finger protein 7,CXXC7,HRX,HTRX1,KMT2A,Lysine N-methyltransferase 2A,Mll,MLL cleavage product C180,MLL1,MLL1,MLL1A,N-terminal cleavage product of 320 kDa,p180,p320,Trithorax-like protein,TRX1,Zinc finger protein HRX
Background: This gene encodes a transcriptional coactivator that plays an essential role in regulating gene expression during early development and hematopoiesis. The encoded protein contains multiple conserved functional domains. One of these domains, the SET domain, is responsible for its histone H3 lysine 4 (H3K4) methyltransferase activity which mediates chromatin modifications associated with epigenetic transcriptional activation. This protein is processed by the enzyme Taspase 1 into two fragments, MLL-C and MLL-N. These fragments reassociate and further assemble into different multiprotein complexes that regulate the transcription of specific target genes, including many of the HOX genes. Multiple chromosomal translocations involving this gene are the cause of certain acute lymphoid leukemias and acute myeloid leukemias. Alternate splicing results in multiple transcript variants.
- 分子量
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Observed_MW: 190kDa
Calculated_MW: 427kDa/431kDa/432kDa
- 基因ID
- 4297
- UniProt
- Q03164
- 途径
- Warburg Effect
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