SQSTM1 抗体
Quick Overview for SQSTM1 抗体 (ABIN6567156)
抗原
See all SQSTM1 抗体适用
宿主
克隆类型
标记
应用范围
质量等级
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特异性
- This antibody ist KO validated.
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纯化方法
- Affinity purification
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免疫原
- Recombinant fusion protein of human SQSTM1 / p62 (NP_001135770.1).
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亚型
- IgG
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应用备注
- WB 1:500-1:2000 IHC 1:50-1:100 IF 1:50-1:100
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- SQSTM1 (Sequestosome 1 (SQSTM1))
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别名
- SQSTM1 / p62
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背景
- This gene encodes a multifunctional protein that binds ubiquitin and regulates activation of the nuclear factor kappa-B (NF-kB) signaling pathway. The protein functions as a scaffolding/adaptor protein in concert with TNF receptor-associated factor 6 to mediate activation of NF-kB in response to upstream signals. Alternatively spliced transcript variants encoding either the same or different isoforms have been identified for this gene. Mutations in this gene result in sporadic and familial Paget disease of bone.
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分子量
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Observed_MW: 62kDa
Calculated_MW: 38kDa/47kDa
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基因ID
- 8878
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UniProt
- Q13501
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途径
- NF-kappaB Signaling, Neurotrophin Signaling Pathway, Autophagy
抗原
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