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SH2D1A 抗体

SH2D1A 适用: 人, 小鼠, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN6567141
发货至: 中国
  • 抗原 See all SH2D1A 抗体
    SH2D1A (SH2 Domain Containing 1A (SH2D1A))
    适用
    • 49
    • 19
    • 19
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    人, 小鼠, 大鼠
    宿主
    • 45
    • 3
    • 1
    • 1
    克隆类型
    • 49
    • 1
    多克隆
    标记
    • 22
    • 5
    • 4
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This SH2D1A antibody is un-conjugated
    应用范围
    • 45
    • 20
    • 13
    • 4
    • 4
    • 3
    • 2
    • 1
    Western Blotting (WB)
    纯化方法
    Affinity purification
    免疫原
    Recombinant protein of human SH2D1A
    亚型
    IgG
    Top Product
    Discover our top product SH2D1A Primary Antibody
  • 应用备注
    WB 1:500 - 1:2000
    限制
    仅限研究用
  • 浓度
    1 mg/mL
    缓冲液
    Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原
    SH2D1A (SH2 Domain Containing 1A (SH2D1A))
    别名
    SH2D1A (SH2D1A 产品)
    别名
    DSHP antibody, EBVS antibody, IMD5 antibody, LYP antibody, MTCP1 antibody, SAP antibody, SAP/SH2D1A antibody, XLP antibody, XLPD antibody, RGD1562408 antibody, Gm686 antibody, SH2D1A antibody, SH2 domain containing 1A antibody, SH2D1A antibody, Sh2d1a antibody
    背景

    Synonyms: DSHP,Duncan disease SH2 protein,Duncan disease SH2-protein,EBVS,IMD5,LYP,MTCP1,SAP,SAP/SH2D1A,SH2 domain containing 1A,SH2 domain protein 1A,SH2 domain-containing protein 1A,SH21A,SH2D1A,Signaling lymphocyte activation molecule associated protein,Signaling lymphocytic activation molecule-associated protein,SLAM associated protein,SLAM associated protein/SH2 domain protein 1A,SLAM-associated protein,T cell signal transduction molecule SAP,T-cell signal transduction molecule SAP,XLP,XLPD

    Background: This gene encodes a protein that plays a major role in the bidirectional stimulation of T and B cells. This protein contains an SH2 domain and a short tail. It associates with the signaling lymphocyte-activation molecule, thereby acting as an inhibitor of this transmembrane protein by blocking the recruitment of the SH2-domain-containing signal-transduction molecule SHP-2 to its docking site. This protein can also bind to other related surface molecules that are expressed on activated T, B and NK cells, thereby modifying signal transduction pathways in these cells. Mutations in this gene cause lymphoproliferative syndrome X-linked type 1 or Duncan disease, a rare immunodeficiency characterized by extreme susceptibility to infection with Epstein-Barr virus, with symptoms including severe mononucleosis and malignant lymphoma. Multiple transcript variants encoding different isoforms have been found for this gene.

    分子量

    Observed_MW: 17kDa

    Calculated_MW: 6kDa/8kDa/13kDa/14kDa

    基因ID
    4068
    UniProt
    O60880
    途径
    Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process
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