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BRAF 抗体

This anti-BRAF antibody is a 兔 多克隆 antibody detecting BRAF in WB. Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN6566465
发货至: 中国

Quick Overview for BRAF 抗体 (ABIN6566465)

抗原

See all BRAF 抗体
BRAF (B-Raf proto-oncogene, serine/threonine kinase (BRAF))

适用

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人, 小鼠, 大鼠

宿主

  • 183
  • 22
  • 2

克隆类型

  • 165
  • 42
多克隆

标记

  • 128
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  • 3
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  • 3
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
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This BRAF antibody is un-conjugated

应用范围

  • 118
  • 114
  • 84
  • 31
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  • 22
  • 13
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Western Blotting (WB)
  • 纯化方法

    Affinity purification

    免疫原

    Recombinant protein of human BRAF

    亚型

    IgG
  • 应用备注

    WB 1:500 - 1:2000

    限制

    仅限研究用
  • 浓度

    1 mg/mL

    缓冲液

    Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原

    BRAF (B-Raf proto-oncogene, serine/threonine kinase (BRAF))

    别名

    BRAF

    背景

    Synonyms: FLJ95109,94 kDa B raf protein,B raf 1,B Raf proto oncogene serine threonine protein kinase,B Raf proto oncogene,serine/threonine kinase,B RAF1,B-Raf proto-oncogene serine/threonine-protein kinase (p94),BRAF 1,BRAF,BRAF,BRAF1,cRmil,MGC126806,MGC138284,Murine sarcoma viral (v-raf) oncogene homolog B1,Murine sarcoma viral v raf oncogene homolog B1,NS7,Oncogen BRAF,oncogene BRAF1,p94,Proto-oncogene B-Raf,Proto-oncogene c-Rmil,RAFB 1,RAFB1,RMIL,Serine/threonine-protein kinase B-raf,v raf murine sarcoma viral oncogene homolog B,v raf murine sarcoma viral oncogene homolog B1,v-Raf murine sarcoma viral oncogene homolog B1

    Background: This gene encodes a protein belonging to the raf/mil family of serine/threonine protein kinases. This protein plays a role in regulating the MAP kinase/ERKs signaling pathway, which affects cell division, differentiation, and secretion. Mutations in this gene are associated with cardiofaciocutaneous syndrome, a disease characterized by heart defects, mental retardation and a distinctive facial appearance. Mutations in this gene have also been associated with various cancers, including non-Hodgkin lymphoma, colorectal cancer, malignant melanoma, thyroid carcinoma, non-small cell lung carcinoma, and adenocarcinoma of lung. A pseudogene, which is located on chromosome X, has been identified for this gene.

    分子量

    Observed_MW: 98kDa

    Calculated_MW: 84kDa

    基因ID

    673

    UniProt

    P15056

    途径

    MAPK Pathway, RTK signaling, Neurotrophin Signaling Pathway, Ribonucleoprotein Complex Subunit Organization, Hepatitis C, Autophagy
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