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HLA-DQA1 抗体 (N-Term)

HLA-DQA1 适用: 人 WB, FACS 宿主: 兔 Polyclonal RB32210 unconjugated
产品编号 ABIN656108
发货至: 中国
  • 抗原 See all HLA-DQA1 抗体
    HLA-DQA1 (Major Histocompatibility Complex, Class II, DQ alpha 1 (HLA-DQA1))
    抗原表位
    • 7
    • 7
    • 7
    • 7
    • 7
    • 6
    • 6
    • 5
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 39-66, N-Term
    适用
    • 65
    • 11
    • 9
    • 1
    宿主
    • 61
    • 4
    克隆类型
    • 51
    • 14
    多克隆
    标记
    • 25
    • 7
    • 7
    • 6
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    This HLA-DQA1 antibody is un-conjugated
    应用范围
    • 44
    • 38
    • 31
    • 10
    • 7
    • 4
    • 2
    • 1
    • 1
    Western Blotting (WB), Flow Cytometry (FACS)
    纯化方法
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    免疫原
    This HLA-DQA1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 39-66 amino acids from the N-terminal region of human HLA-DQA1.
    克隆位点
    RB32210
    亚型
    Ig Fraction
    Top Product
    Discover our top product HLA-DQA1 Primary Antibody
  • 应用备注
    WB: 1:1000. WB: 1:1000. WB: 1:1000. FC: 1:10~50
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
    有效期
    6 months
  • 抗原
    HLA-DQA1 (Major Histocompatibility Complex, Class II, DQ alpha 1 (HLA-DQA1))
    别名
    HLA-DQA1 (HLA-DQA1 产品)
    别名
    CD antibody, CELIAC1 antibody, DQ-A1 antibody, GSE antibody, HLA-DQA antibody, BoLA-DQA antibody, hla-dqa1 antibody, major histocompatibility complex, class II, DQ alpha 1 antibody, major histocompatibility complex, class II, DQ alpha, type 1 antibody, major histocompatibility complex, class II, DQ alpha 1 L homeolog antibody, HLA-DQA1 antibody, BOLA-DQA1 antibody, hla-dqa1.L antibody
    背景
    HLA-DQA1 belongs to the HLA class II alpha chain paralogues. The class II molecule is a heterodimer consisting of an alpha (DQA) and a beta chain (DQB), both anchored in the membrane. It plays a central role in the immune system by presenting peptides derived from extracellular proteins. Class II molecules are expressed in antigen presenting cells (APC: B Lymphocytes, dendritic cells, macrophages). The alpha chain is approximately 33-35 kDa. It is encoded by 5 exons, exon 1 encodes the leader peptide, exons 2 and 3 encode the two extracellular domains, and exon 4 encodes the transmembrane domain and the cytoplasmic tail. Within the DQ molecule both the alpha chain and the beta chain contain the polymorphisms specifying the peptide binding specificities, resulting in up to four different molecules. Typing for these polymorphisms is routinely done for bone marrow transplantation.
    分子量
    27805
    基因ID
    3117
    NCBI登录号
    NP_002113
    UniProt
    P01909
    途径
    TCR Signaling, Cancer Immune Checkpoints
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