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CYP1A2 抗体 (AA 255-282)

CYP1A2 适用: 人, 小鼠 WB, IF, IHC (p) 宿主: 兔 Polyclonal RB16939 unconjugated
产品编号 ABIN655272
发货至: 中国
  • 抗原 See all CYP1A2 抗体
    CYP1A2 (Cytochrome P450, Family 1, Subfamily A, Polypeptide 2 (CYP1A2))
    抗原表位
    • 16
    • 8
    • 8
    • 7
    • 6
    • 5
    • 4
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 255-282
    适用
    • 63
    • 29
    • 23
    人, 小鼠
    宿主
    • 51
    • 13
    • 2
    克隆类型
    • 54
    • 12
    多克隆
    标记
    • 35
    • 6
    • 5
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This CYP1A2 antibody is un-conjugated
    应用范围
    • 56
    • 33
    • 23
    • 17
    • 17
    • 13
    • 13
    • 8
    • 7
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    纯化方法
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    免疫原
    This CYP1A2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 255-282 amino acids from the Central region of human CYP1A2.
    克隆位点
    RB16939
    亚型
    Ig Fraction
    Top Product
    Discover our top product CYP1A2 Primary Antibody
  • 应用备注
    IF: 1:10~50. WB: 1:1000. IHC-P: 1:10~50
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
    有效期
    6 months
  • Sriwattanapong, Slocum, Chawanthayatham, Fedeles, Egner, Groopman, Satayavivad, Croy, Essigmann: "Editor's Highlight: Pregnancy Alters Aflatoxin B1 Metabolism and Increases DNA Damage in Mouse Liver." in: Toxicological sciences : an official journal of the Society of Toxicology, Vol. 160, Issue 1, pp. 173-179, (2018) (PubMed).

    Okamatsu, Kawakami, Komatsu, Kitazawa, Uno, Teraoka: "Functional expression and comparative characterization of four feline P450 cytochromes using fluorescent substrates." in: Xenobiotica; the fate of foreign compounds in biological systems, Vol. 47, Issue 11, pp. 951-961, (2017) (PubMed).

  • 抗原
    CYP1A2 (Cytochrome P450, Family 1, Subfamily A, Polypeptide 2 (CYP1A2))
    别名
    CYP1A2 (CYP1A2 产品)
    别名
    CP12 antibody, P3-450 antibody, P450(PA) antibody, CYP1A2 antibody, CYPIA2 antibody, P450-PM4 antibody, Cyp1a1 antibody, P450-3 antibody, CYPD45 antibody, P-450d antibody, RATCYPD45 antibody, CYP1A5 antibody, CP450 antibody, CYP-IA2 antibody, cytochrome P450 family 1 subfamily A member 2 antibody, cytochrome P450 1A2 antibody, cytochrome P450 LM4 antibody, cytochrome P450, family 1, subfamily A, polypeptide 2 antibody, cytochrome P450, family 1, subfamily a, polypeptide 2 antibody, cytochrome P450 1A2-like antibody, CYP1A2 antibody, LOC100328937 antibody, Cyp1a2 antibody, VDBG_06455 antibody, LOC101825565 antibody, LOC102130662 antibody
    背景
    This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. The protein encoded by this gene localizes to the endoplasmic reticulum and its expression is induced by some polycyclic aromatic hydrocarbons (PAHs), some of which are found in cigarette smoke. The enzyme's endogenous substrate is unknown, however, it is able to metabolize some PAHs to carcinogenic intermediates. Other xenobiotic substrates for this enzyme include caffeine, aflatoxin B1, and acetaminophen. The transcript from this gene contains four Alu sequences flanked by direct repeats in the 3' untranslated region.
    分子量
    58407
    基因ID
    1544
    NCBI登录号
    NP_000752
    UniProt
    P05177
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