CYP1A2 抗体 (AA 185-320)
(2 references)-
- 抗原 See all CYP1A2 抗体
- CYP1A2 (Cytochrome P450, Family 1, Subfamily A, Polypeptide 2 (CYP1A2))
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抗原表位
- AA 185-320
- 适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This CYP1A2 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 原理
- Rabbit IgG polyclonal antibody for Cytochrome P450 1A2(CYP1A2) detection. Tested with WB, IHC-P in Human,Mouse,Rat.
- 交叉反应 （详细）
- No cross reactivity with other proteins.
- 产品特性
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Rabbit IgG polyclonal antibody for Cytochrome P450 1A2(CYP1A2) detection. Tested with WB, IHC-P in Human,Mouse,Rat.
Gene Name: cytochrome P450, family 1, subfamily A, polypeptide 2
Protein Name: Cytochrome P450 1A2 - 纯化方法
- Immunogen affinity purified.
- 免疫原
- E.coli-derived human CYP1A2 recombinant protein (Position: H185-D320). Human CYP1A2 shares 69.9% and 72.1% amino acid (aa) sequence identity with mouse and rat CYP1A2, respectively.
- 亚型
- IgG
- Top Product
- Discover our top product CYP1A2 Primary Antibody
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anti-Cytochrome P450, Family 1, Subfamily A, Polypeptide 2 (CYP1A2) antibody
CYP1A2 适用: 人 WB, IHC, IF, FACS, IHC (p) 宿主: 小鼠 Monoclonal 7D12 unconjugated
anti-Cytochrome P450, Family 1, Subfamily A, Polypeptide 2 (CYP1A2) (AA 211-310) antibodyCYP1A2 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 4B3 unconjugated
anti-Cytochrome P450, Family 1, Subfamily A, Polypeptide 2 (CYP1A2) (AA 255-282) antibodyCYP1A2 适用: 人, 小鼠 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Cytochrome P450, Family 1, Subfamily A, Polypeptide 2 (CYP1A2) (AA 221-320) antibodyCYP1A2 适用: 人, 小鼠, 大鼠 WB, ELISA, FACS, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Cytochrome P450, Family 1, Subfamily A, Polypeptide 2 (CYP1A2) (AA 192-444) antibodyCYP1A2 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Cytochrome P450, Family 1, Subfamily A, Polypeptide 2 (CYP1A2) antibodyCYP1A2 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Cytochrome P450, Family 1, Subfamily A, Polypeptide 2 (CYP1A2) (AA 255-282) antibodyCYP1A2 适用: 人, 小鼠 WB, IF, IHC (p) 宿主: 兔 Polyclonal RB16939 unconjugated
anti-Cytochrome P450, Family 1, Subfamily A, Polypeptide 2 (CYP1A2) antibodyCYP1A2 适用: 人 WB, ELISA, IHC 宿主: 兔 Monoclonal 8B2 unconjugated Recombinant Antibody
anti-Cytochrome P450, Family 1, Subfamily A, Polypeptide 2 (CYP1A2) (AA 211-310) antibodyCYP1A2 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Cytochrome P450, Family 1, Subfamily A, Polypeptide 2 (CYP1A2) (Internal Region) antibodyVerified CYP1A2 适用: 人, 小鼠, 大鼠 WB, ELISA 宿主: 山羊 Polyclonal unconjugated
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- 应用备注
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WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Mouse, Rat, Predicted Species: Human
IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Human, Mouse, Rat, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
Notes: Tested Species: Species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities. Other applications have not been tested. Optimal dilutions should be determined by end users. - 说明
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Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
- 浓度
- 500 μg/mL
- 缓冲液
- Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freezing and thawing.
- 储存条件
- 4 °C/-20 °C
- 储存方法
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At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
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: "Wuzhi tablet (Schisandra Sphenanthera extract) protects against acetaminophen-induced hepatotoxicity by inhibition of CYP-mediated bioactivation and regulation of NRF2-ARE and p53/p21 pathways." in: Drug metabolism and disposition: the biological fate of chemicals, Vol. 42, Issue 12, pp. 1982-90, (2014) (PubMed).
: "Schisandrol B protects against acetaminophen-induced hepatotoxicity by inhibition of CYP-mediated bioactivation and regulation of liver regeneration." in: Toxicological sciences : an official journal of the Society of Toxicology, Vol. 143, Issue 1, pp. 107-15, (2014) (PubMed).
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: "Wuzhi tablet (Schisandra Sphenanthera extract) protects against acetaminophen-induced hepatotoxicity by inhibition of CYP-mediated bioactivation and regulation of NRF2-ARE and p53/p21 pathways." in: Drug metabolism and disposition: the biological fate of chemicals, Vol. 42, Issue 12, pp. 1982-90, (2014) (PubMed).
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- 抗原
- CYP1A2 (Cytochrome P450, Family 1, Subfamily A, Polypeptide 2 (CYP1A2))
- 别名
- CYP1A2 (CYP1A2 产品)
- 别名
- CP12 antibody, P3-450 antibody, P450(PA) antibody, CYP1A2 antibody, CYPIA2 antibody, P450-PM4 antibody, Cyp1a1 antibody, P450-3 antibody, CYPD45 antibody, P-450d antibody, RATCYPD45 antibody, CYP1A5 antibody, CP450 antibody, CYP-IA2 antibody, cytochrome P450 family 1 subfamily A member 2 antibody, cytochrome P450 1A2 antibody, cytochrome P450 LM4 antibody, cytochrome P450, family 1, subfamily A, polypeptide 2 antibody, cytochrome P450, family 1, subfamily a, polypeptide 2 antibody, cytochrome P450 1A2-like antibody, CYP1A2 antibody, LOC100328937 antibody, Cyp1a2 antibody, VDBG_06455 antibody, LOC101825565 antibody, LOC102130662 antibody
- 背景
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CYP1A2 (Cytochrome P450, Subfamily I, Polypeptide 2) is a member of the cytochrome P450 mixed-function oxidase system and is involved in the metabolism of xenobiotics in the body. CYP1A2 is a member of the cytochrome P450 superfamily of enzymes. In humans, the CYP1A2 enzyme is encoded by the CYP1A2 gene. CYP1A2 localizes to the endoplasmic reticulum and its expression is induced by some polycyclic aromatic hydrocarbons (PAHs), some of which are found in cigarette smoke. The CYP1A2 gene encodes a P450 enzyme involved in O-deethylation of phenacetin. Ikeya et al. (1989) found that the human CYP1A2 gene spans almost 7.8 kb and contains 7 exons. The CYP1A2 gene is mapped on 15q24.1. CYP1A2 accounts for nearly 15 % of the cytochrome P450 in the human liver. CYP1A2 displays higher activity in men than in women, and is inhibited by oral contraceptives. Inducers of CYP1A2 include cruciferous vegetables. Cigarette smoking has also been shown to increase CYP1A2 activity. Expression of CYP1A2 appears to be induced by various dietary constituents.
Synonyms: Aryl hydrocarbon hydroxylase antibody|CP 12 antibody|CP12 antibody|CP1A2_HUMAN antibody| CYP1A2 antibody|CYPIA2 antibody|Cytochrome P(3)450 antibody|Cytochrome P450 1A2 antibody| Cytochrome P450 4 antibody|Cytochrome P450 family 1 polypeptide 2 antibody|Cytochrome P450 family 1 subfamily A polypeptide 2 antibody|Cytochrome P450 subfamily I aromatic compound inducible polypeptide 2 antibody|Cytochrome P450-P3 antibody|Cytochrome P4501A2 antibody| Dioxin inducable P3 450 antibody|Flavoprotein linked monooxygenase antibody|Microsomal monooxygenase antibody|P(3)450 antibody|P3 450 antibody|P450 4 antibody|P450 form 4 antibody|P450 P3 antibody|P450(PA) antibody|Xenobiotic monooxygenase antibody - 基因ID
- 1544
- UniProt
- P05177
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