NR1H3 抗体 (AA 226-253)
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- 抗原 See all NR1H3 抗体
- NR1H3 (Nuclear Receptor Subfamily 1, Group H, Member 3 (NR1H3))
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抗原表位
- AA 226-253
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This NR1H3 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Flow Cytometry (FACS), Immunofluorescence (IF)
- 纯化方法
- This antibody is purified through a protein A column, followed by peptide affinity purification.
- 免疫原
- This NR1H3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 226-253 amino acids from the Central region of human NR1H3.
- 克隆位点
- RB23158
- 亚型
- Ig Fraction
- Top Product
- Discover our top product NR1H3 Primary Antibody
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- 应用备注
- IF: 1:10~50. WB: 1:1000. FC: 1:10~50
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
- 有效期
- 6 months
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- 抗原
- NR1H3 (Nuclear Receptor Subfamily 1, Group H, Member 3 (NR1H3))
- 别名
- NR1H3 (NR1H3 产品)
- 别名
- NR1H3 antibody, LXR-a antibody, LXRA antibody, RLD-1 antibody, AU018371 antibody, LXR antibody, RLD1 antibody, Unr1 antibody, LXRalpha antibody, LXR-alpha antibody, im:7141239 antibody, wu:fd59b01 antibody, zgc:113339 antibody, zgc:158542 antibody, nuclear receptor subfamily 1 group H member 3 antibody, nuclear receptor subfamily 1, group H, member 3 antibody, NR1H3 antibody, nr1h3 antibody, Nr1h3 antibody
- 背景
- NR1H3 form a subfamily of the nuclear receptor superfamily and are key regulators of macrophage function, controlling transcriptional programs involved in lipid homeostasis and inflammation. The inducible LXRA is highly expressed in liver, adrenal gland, intestine, adipose tissue, macrophages, lung, and kidney, whereas LXRB is ubiquitously expressed. Ligand-activated LXRs form obligate heterodimers with retinoid X receptors (RXRs, see MIM 180245) and regulate expression of target genes containing LXR response elements.
- 分子量
- 50396
- 基因ID
- 10062
- NCBI登录号
- NP_001123573, NP_001123574, NP_005684
- UniProt
- Q13133
- 途径
- Nuclear Receptor Transcription Pathway, Steroid Hormone Mediated Signaling Pathway, Nuclear Hormone Receptor Binding, Cellular Response to Molecule of Bacterial Origin, Hepatitis C
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