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MCM2 抗体 (C-Term)

The 兔 多克隆 anti-MCM2 antibody is suitable to detect MCM2 in samples from 人 和 小鼠. It has been validated for WB 和 IHC (p).
产品编号 ABIN653324
发货至: 中国
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中国
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for MCM2 抗体 (C-Term) (ABIN653324)

抗原

See all MCM2 抗体
MCM2 (Minichromosome Maintenance Complex Component 2 (MCM2))

适用

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人, 小鼠

宿主

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克隆类型

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多克隆

标记

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This MCM2 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

克隆位点

RB25168
  • 抗原表位

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    AA 649-677, C-Term

    预测反应

    X

    纯化方法

    This antibody is purified through a protein A column, followed by peptide affinity purification.

    免疫原

    This MCM2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 649-677 amino acids from the C-terminal region of human MCM2.

    亚型

    Ig Fraction
  • 应用备注

    WB: 1:1000. WB: 1:2000. IHC-P: 1:50~100

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

    有效期

    6 months
  • 抗原

    MCM2 (Minichromosome Maintenance Complex Component 2 (MCM2))

    别名

    MCM2

    背景

    MCM2 is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are involved in the initiation of eukaryotic genome replication. The hexameric protein complex formed by MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. This protein forms a complex with MCM4, 6, and 7, and has been shown to regulate the helicase activity of the complex. This protein is phosphorylated, and thus regulated by, protein kinases CDC2 and CDC7.

    分子量

    101896

    基因ID

    4171

    NCBI登录号

    NP_004517

    UniProt

    P49736

    途径

    DNA Damage Repair, Mitotic G1-G1/S Phases, DNA Replication, Chromatin Binding, Synthesis of DNA
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