NLRP3 抗体 (N-Term)
(3 references)-
- 抗原 See all NLRP3 抗体
- NLRP3 (NLR Family, Pyrin Domain Containing 3 (NLRP3))
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抗原表位
- AA 65-91, N-Term
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This NLRP3 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 纯化方法
- This antibody is purified through a protein A column, followed by peptide affinity purification.
- 免疫原
- This NLRP3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 65-91 amino acids from the N-terminal region of human NLRP3.
- 克隆位点
- RB22404
- 亚型
- Ig Fraction
- Top Product
- Discover our top product NLRP3 Primary Antibody
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anti-NLR Family, Pyrin Domain Containing 3 (NLRP3) (AA 1-93), (Pyrin Domain) antibody
NLRP3 适用: 人, 小鼠 WB, IHC, IF, IP 宿主: 小鼠 Monoclonal Cryo-2 unconjugated
anti-NLR Family, Pyrin Domain Containing 3 (NLRP3) (AA 15-120) antibodyNLRP3 适用: 人, 小鼠, 大鼠, 犬 WB, ELISA, IHC (p), FACS, ICC, IHC (fro), IF (p), IF (cc) 宿主: 兔 Polyclonal unconjugated
anti-NLR Family, Pyrin Domain Containing 3 (NLRP3) (AA 671-1033) antibodyNLRP3 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-NLR Family, Pyrin Domain Containing 3 (NLRP3) (C-Term) antibodyVerified NLRP3 适用: 人 ELISA, IHC, IF, FACS 宿主: 山羊 Polyclonal unconjugated
anti-NLR Family, Pyrin Domain Containing 3 (NLRP3) (C-Term) antibodyNLRP3 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-NLR Family, Pyrin Domain Containing 3 (NLRP3) (N-Term) antibodyNLRP3 适用: 人, 小鼠, 大鼠 WB, IF, IHC (p), FACS, ICC 宿主: 兔 Polyclonal unconjugated
anti-NLR Family, Pyrin Domain Containing 3 (NLRP3) (AA 12-31), (N-Term) antibodyNLRP3 适用: 人, 大鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-NLR Family, Pyrin Domain Containing 3 (NLRP3) (AA 30-102) antibodyNLRP3 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-NLR Family, Pyrin Domain Containing 3 (NLRP3) (AA 1-100) antibodyNLRP3 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 3B1 unconjugated
anti-NLR Family, Pyrin Domain Containing 3 (NLRP3) (AA 21-194) antibodyNLRP3 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- WB: 1:1000-1:2000. IHC-P: 1:10~50
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
- 有效期
- 6 months
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: "Effects of Berberine on NLRP3 and IL-1β Expressions in Monocytic THP-1 Cells with Monosodium Urate Crystals-Induced Inflammation." in: BioMed research international, Vol. 2016, pp. 2503703, (2016) (PubMed).
: "Protective Effects of Catechin against Monosodium Urate-Induced Inflammation through the Modulation of NLRP3 Inflammasome Activation." in: Journal of agricultural and food chemistry, (2015) (PubMed).
: "Effects of Modified Simiao Decoction on IL-1 β and TNF α Secretion in Monocytic THP-1 Cells with Monosodium Urate Crystals-Induced Inflammation." in: Evidence-based complementary and alternative medicine : eCAM, Vol. 2014, pp. 406816, (2014) (PubMed).
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: "Effects of Berberine on NLRP3 and IL-1β Expressions in Monocytic THP-1 Cells with Monosodium Urate Crystals-Induced Inflammation." in: BioMed research international, Vol. 2016, pp. 2503703, (2016) (PubMed).
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- 抗原
- NLRP3 (NLR Family, Pyrin Domain Containing 3 (NLRP3))
- 别名
- NLRP3 (NLRP3 产品)
- 背景
- NLRP3 is a pyrin-like protein containing a pyrin domain, a nucleotide-binding site (NBS) domain, and a leucine-rich repeat (LRR) motif. This protein interacts with the apoptosis-associated speck-like protein PYCARD/ASC, which contains a caspase recruitment domain, and is a member of the NALP3 inflammasome complex. This complex functions as an upstream activator of NF-kappaB signaling, and it plays a role in the regulation of inflammation, the immune response, and apoptosis.
- 分子量
- 118173
- 基因ID
- 114548
- NCBI登录号
- NP_001073289, NP_001120933, NP_001120934, NP_001230062, NP_004886, NP_899632
- UniProt
- Q96P20
- 途径
- Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Endopeptidase Activity, Inflammasome
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