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P2RX7 抗体 (AA 563-592)

P2RX7 适用: 人, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal RB21714 unconjugated
产品编号 ABIN651861
发货至: 中国
  • 抗原 See all P2RX7 抗体
    P2RX7 (Purinergic Receptor P2X, Ligand-Gated Ion Channel, 7 (P2RX7))
    抗原表位
    • 15
    • 11
    • 6
    • 5
    • 5
    • 5
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 563-592
    适用
    • 57
    • 39
    • 19
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    人, 小鼠
    宿主
    • 56
    • 2
    • 2
    • 1
    克隆类型
    • 57
    • 4
    多克隆
    标记
    • 27
    • 7
    • 4
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This P2RX7 antibody is un-conjugated
    应用范围
    • 47
    • 26
    • 23
    • 13
    • 13
    • 12
    • 10
    • 9
    • 5
    • 4
    • 3
    • 3
    • 2
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    纯化方法
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    免疫原
    This P2RX7 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 563-592 amino acids of human P2RX7.
    克隆位点
    RB21714
    亚型
    IgG
    Top Product
    Discover our top product P2RX7 Primary Antibody
  • 应用备注
    WB: 1:1000. IHC-P: 1:50~100
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
    有效期
    6 months
  • Deng, Guo, Yuan, Shang, Zhu, Liu: "P2X7 Receptor Antagonism Attenuates the Intermittent Hypoxia-induced Spatial Deficits in a Murine Model of Sleep Apnea Via Inhibiting Neuroinflammation and Oxidative Stress." in: Chinese medical journal, Vol. 128, Issue 16, pp. 2168-75, (2015) (PubMed).

  • 抗原
    P2RX7 (Purinergic Receptor P2X, Ligand-Gated Ion Channel, 7 (P2RX7))
    别名
    P2RX7 (P2RX7 产品)
    别名
    p2xr7 antibody, P2RX7 antibody, P2X7 antibody, AI467586 antibody, P2X(7) antibody, P2X7R antibody, p2x7 antibody, purinergic receptor P2X 7 antibody, purinergic receptor P2X, ligand-gated ion channel, 7 antibody, P2X purinoceptor 7 antibody, P2RX7 antibody, p2rx7 antibody, LOC100458463 antibody, P2rx7 antibody
    背景
    P2RX7 belongs to the family of purinoceptors for ATP. This receptor functions as a ligand-gated ion channel and is responsible for ATP-dependent lysis of macrophages through the formation of membrane pores permeable to large molecules. Activation of this nuclear receptor by ATP in the cytoplasm may be a mechanism by which cellular activity can be coupled to changes in gene expression.
    分子量
    68585
    基因ID
    5027
    NCBI登录号
    NP_002553
    UniProt
    Q99572
    途径
    Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Synaptic Vesicle Exocytosis
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